An Epigenetic Signature of Species Maximum Life Span

Source https://www.fightaging.org/archives/2024/06/an-epigenetic-signature-of-species-maximum-life-span/

Self evidently, differences in species life span are determined by genetic differences. It is intriguing, however, to see that it is possible to produce an epigenetic signatures of species life span in mammals. Epigenetic marks on and around the genome determine gene expression, the degree to which a given protein is produced from a given gene sequence. That an epigenetic signature of maximum life span can be determined in mammals indicates that differences in the expression of specific genes (most likely many, many specific genes) are an important component of species longevity, even in cases where the proteins are very similar in structure and function between species, and even given that these epigenetic differences must ultimately descend from differences in the genome.

By analyzing…

Source https://www.fightaging.org/archives/2024/06/an-epigenetic-signature-of-species-maximum-life-span/

Self evidently, differences in species life span are determined by genetic differences. It is intriguing, however, to see that it is possible to produce an epigenetic signatures of species life span in mammals. Epigenetic marks on and around the genome determine gene expression, the degree to which a given protein is produced from a given gene sequence. That an epigenetic signature of maximum life span can be determined in mammals indicates that differences in the expression of specific genes (most likely many, many specific genes) are an important component of species longevity, even in cases where the proteins are very similar in structure and function between species, and even given that these epigenetic differences must ultimately descend from differences in the genome.

By analyzing…

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