Cancers Subvert the Immune System to Create a Protective Population of Regulatory T Cells

Source https://www.fightaging.org/archives/2022/08/cancers-subvert-the-immune-system-to-create-a-protective-population-of-regulatory-t-cells/

Researchers here identify distinctive markers for a population of regulatory T cells that act to protect at least some types of tumor tissue from the rest of the immune system. Cancers subvert the immune system in a range of ways, making it blind to cancer cells, and even making immune cells assist in the growth of the cancer. In principle destroying these protective, subverted immune cells could produce a renewed attack on a tumor, or at the very least make it more vulnerable to present therapies, particularly those that encourage immune cells to attack cancer cells.

Some types of T cells work to calm their over-active brethren. Known as regulatory T cells, or T-regs, they typically tamp down inflammation, quieting that mob a…

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