Cellular Processes Involved in Brain Aging

Source https://www.fightaging.org/archives/2021/07/cellular-processes-involved-in-brain-aging/

The paper here is a representative example of much of the mainstream of research into aging, in that it is focused on processes that are well downstream of the causes of aging. In effect they are mechanistic symptoms of aging, the taxonomy of disruptions to the normal operation of cells and tissues that is the result of the underlying processes of damage accumulation that drive aging. It is likely that focusing on downstream outcomes of aging will result in an expensive path to poor therapies, at least in comparison to a focus on the underlying causes of these outcomes. The results of damage are more complicated to understand and address than the damage itself. Further, preventing the outcomes of damage without actually trying to repair the damage itself is likely to be somewhere between hard and impossible to achieve.

Aging is the leading risk factor for several age-associated diseases su…

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