Source https://www.fightaging.org/archives/2025/07/cellular-senescence-in-osteoblasts-as-a-contributing-cause-of-osteoporosis/
Cells that become senescent cease to replicate and secrete inflammatory signals that are disruptive to tissue structure and function. This happens constantly throughout life, largely as the result of cells reaching the Hayflick limit on replication, but also as a result of stress, damage, or a toxic local environment. In youth, newly created senescent cells are cleared rapidly by the immune system. With age, this clearance is impaired and the number of senescent cells in every cell population increases, contributing to age-related dysfunction and disease.
In today’s open access paper, researchers discuss the biochemistry and role of…
Source https://www.fightaging.org/archives/2025/07/cellular-senescence-in-osteoblasts-as-a-contributing-cause-of-osteoporosis/
Cells that become senescent cease to replicate and secrete inflammatory signals that are disruptive to tissue structure and function. This happens constantly throughout life, largely as the result of cells reaching the Hayflick limit on replication, but also as a result of stress, damage, or a toxic local environment. In youth, newly created senescent cells are cleared rapidly by the immune system. With age, this clearance is impaired and the number of senescent cells in every cell population increases, contributing to age-related dysfunction and disease.
In today’s open access paper, researchers discuss the biochemistry and role of…
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