In today’s open access paper, researchers report on correlations between phenotypic age and cognitive function in older adults. Phenotypic age is an aging clock that uses a small number of blood chemistry measures as its inputs, such as portions of a complete blood count, creatine, C-reactive protein, and so forth. The big advantage of this approach over epigenetic clocks is that one can look at what changed following an intervention and theorize a little about what that means. Did C-reactive protein levels go down in the course of a reduction in phenotypic age, for example? That indicates positive effects on the <a href="https://www.fi…
Chronological Age Doesn't Correlate Well with Cognitive Decline
In today’s open access paper, researchers report on correlations between phenotypic age and cognitive function in older adults. Phenotypic age is an aging clock that uses a small number of blood chemistry measures as its inputs, such as portions of a complete blood count, creatine, C-reactive protein, and so forth. The big advantage of this approach over epigenetic clocks is that one can look at what changed following an intervention and theorize a little about what that means. Did C-reactive protein levels go down in the course of a reduction in phenotypic age, for example? That indicates positive effects on the <a href="https://www.fi…