CISD2 Slows the Age-Related Dysfunction of Heart Muscle

Source https://www.fightaging.org/archives/2025/08/cisd2-slows-the-age-related-dysfunction-of-heart-muscle/

Increased CISD2 expression has been shown to slow aging in mice, and is one of the few longevity-inducing genes robustly identified to date. Increased expression improves liver function, reduces senescent cell inflammatory signaling in skin, and generates a range of other beneficial effects along the way. CISD2 produces numerous changes in aspects of metabolism, including mitochondrial func…

Source https://www.fightaging.org/archives/2025/08/cisd2-slows-the-age-related-dysfunction-of-heart-muscle/

Increased CISD2 expression has been shown to slow aging in mice, and is one of the few longevity-inducing genes robustly identified to date. Increased expression improves liver function, reduces senescent cell inflammatory signaling in skin, and generates a range of other beneficial effects along the way. CISD2 produces numerous changes in aspects of metabolism, including mitochondrial func…

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