Confirming Adult Human Neurogenesis in the Hippocampus

Source https://www.fightaging.org/archives/2025/07/confirming-adult-human-neurogenesis-in-the-hippocampus/

It has long been established in mice that adult animals exhibit neurogenesis in the brain, the creation of new neurons that integrate into existing neural networks. There remains some debate over whether new neurons are created in the adult human brain, however, despite the consensus being that it would be unexpected to find that humans differ from mice in this way. Neurogenesis is thought to be essential to the function of learning and memory. That this process does occur would in principle make it easier to produce regenerative therapies that generate new neurons in the living brain to restore lost function. Establishing beyond doubt that this neurogenesis occurs in living humans brains has been challenging for a number of technical and logistical reasons. Nonetheless, progress has been made in establishing the necessary d…

Source https://www.fightaging.org/archives/2025/07/confirming-adult-human-neurogenesis-in-the-hippocampus/

It has long been established in mice that adult animals exhibit neurogenesis in the brain, the creation of new neurons that integrate into existing neural networks. There remains some debate over whether new neurons are created in the adult human brain, however, despite the consensus being that it would be unexpected to find that humans differ from mice in this way. Neurogenesis is thought to be essential to the function of learning and memory. That this process does occur would in principle make it easier to produce regenerative therapies that generate new neurons in the living brain to restore lost function. Establishing beyond doubt that this neurogenesis occurs in living humans brains has been challenging for a number of technical and logistical reasons. Nonetheless, progress has been made in establishing the necessary d…

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