Source https://www.fightaging.org/archives/2024/06/ddx5-can-form-prion-like-aggregates-in-the-aging-brain/
A prion is a protein that can misfold in a way that encourages other molecules of the same protein to misfold in the same way. It can thus spread like a pathogen through cells and tissues, producing pathological changes in its wake. “Prion” is a term used inconsistently in the research community, as the very well researched amyloid-β and α-synuclein, drivers of neurodegenerative conditions, have prion-like properties but are rarely referred to as prions. So in one sense, yes, there are indeed prions in the aging brain, spreading and causing harm. Here, researchers look into the protein DDX5 in s…
Source https://www.fightaging.org/archives/2024/06/ddx5-can-form-prion-like-aggregates-in-the-aging-brain/
A prion is a protein that can misfold in a way that encourages other molecules of the same protein to misfold in the same way. It can thus spread like a pathogen through cells and tissues, producing pathological changes in its wake. “Prion” is a term used inconsistently in the research community, as the very well researched amyloid-β and α-synuclein, drivers of neurodegenerative conditions, have prion-like properties but are rarely referred to as prions. So in one sense, yes, there are indeed prions in the aging brain, spreading and causing harm. Here, researchers look into the protein DDX5 in s…
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