Dysfunctional Mitophagy in the Aging Brain

Source https://www.fightaging.org/archives/2021/10/dysfunctional-mitophagy-in-the-aging-brain/

Every cell in the body contains hundreds of mitochondria, the evolved descendants of ancient symbiotic bacteria. Their primary purpose is to produce adenosine triphosphate (ATP), an energy store molecule used to power cellular operations. They are also involved in a great many other aspects of cell function, however. Mitochondria are dynamic organelles, capable of fusing together, passing component parts between one another, and replicating like bacteria. A cell regulates mitochondrial function in part through mitophagy, an autophagy process that breaks down and recycles mitochondria when they become worn and damaged.

Mitochondrial function is understandably vital to cell function. Wit…

Source https://www.fightaging.org/archives/2021/10/dysfunctional-mitophagy-in-the-aging-brain/

Every cell in the body contains hundreds of mitochondria, the evolved descendants of ancient symbiotic bacteria. Their primary purpose is to produce adenosine triphosphate (ATP), an energy store molecule used to power cellular operations. They are also involved in a great many other aspects of cell function, however. Mitochondria are dynamic organelles, capable of fusing together, passing component parts between one another, and replicating like bacteria. A cell regulates mitochondrial function in part through mitophagy, an autophagy process that breaks down and recycles mitochondria when they become worn and damaged.

Mitochondrial function is understandably vital to cell function. Wit…

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