Early Life Exercise Improves Healthspan But Not Lifespan in Mice

Source https://www.fightaging.org/archives/2025/07/early-life-exercise-improves-healthspan-but-not-lifespan-in-mice/

Exercise is demonstrably beneficial, but does little to lengthen maximum life span in mice. It does compress morbidity, in the sense of extending the period of healthy life and increasing median life span without increasing maximum life span. The study noted here is an example of this sort of outcome. Mice were put through a program of exercise in early life, roughly equivalent of teenage human years through to mid-20s, and were shown to have a longer healthspan but not a longer lifespan. This might suggest that exercise affects many of the forms of damage and dysfunction that cause aging, but that there are some processes it has little effect on. It is the consequences of the unaffected processes that eventually produce mortality, regardless of a slowing of other aspects of aging.

It is well-known that physical activity exerts health benefi…

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