Investigating the Ability of Type 2 Diabetes Treatments to Modestly Slow Aging Extends to SGLT-2 Inhibitors

Source https://www.fightaging.org/archives/2022/11/investigating-the-ability-of-type-2-diabetes-treatments-to-modestly-slow-aging-extends-to-sglt-2-inhibitors/

There is something of a trend towards picking over the landscape of type 2 diabetes medication in search of therapies that can modestly slow aging, at least in animal models. If metformin is anything to go by, we shouldn’t be at all optimistic that this will result in useful outcomes in humans. “Useful” in this context means reliable gains in late life health and life expectancy in metabolically normal people, where those gains are larger than those that can be achieved with exercise, and with minimal side-effects. Otherwise, this seems like time and effort that could be directed to more productive areas of research and development.

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