The blood-brain barrier is a layer of specialized cells wrapping blood vessels in the central nervous system, isolating the brain from the rest of the body by allowing on some cells and molecules to pass. The blood-brain barrier becomes leaky with age, however, as vascular dysfunction progresses. This allows inappropriate molecules into the brain to provoke inflammatory responses from brain-resident immune cells, and no doubt produces other detrimental consequences as well. Researchers do not consider it settled that blood-brain barrier dysfunction is a deeper cause of <a href="h…
Is Blood-Brain Barrier Dysfunction Cause or Consequence in Alzheimer's Disease Pathology?
The blood-brain barrier is a layer of specialized cells wrapping blood vessels in the central nervous system, isolating the brain from the rest of the body by allowing on some cells and molecules to pass. The blood-brain barrier becomes leaky with age, however, as vascular dysfunction progresses. This allows inappropriate molecules into the brain to provoke inflammatory responses from brain-resident immune cells, and no doubt produces other detrimental consequences as well. Researchers do not consider it settled that blood-brain barrier dysfunction is a deeper cause of <a href="h…