Source https://www.fightaging.org/archives/2019/10/leptin-as-the-link-between-obesity-and-hypertension/
Hypertension, chronically raised blood pressure, is very damaging. It is an important mechanism by which low-level molecular damage and disarray in aging is converted into structural damage to important tissues in the brain, kidneys, and other organs. It is so influential in aging that lowering of raised blood pressure reduces mortality and disease risk even without addressing the underlying causes of the condition. Obesity is well known to cause raised blood pressure, and researchers here identify a novel mechanism for this effect involving leptin signaling. Since leptin signaling does change with age, it will be interesting to see whether or not this mechanism also operates to a significant degree in the…
Source https://www.fightaging.org/archives/2019/10/leptin-as-the-link-between-obesity-and-hypertension/
Hypertension, chronically raised blood pressure, is very damaging. It is an important mechanism by which low-level molecular damage and disarray in aging is converted into structural damage to important tissues in the brain, kidneys, and other organs. It is so influential in aging that lowering of raised blood pressure reduces mortality and disease risk even without addressing the underlying causes of the condition. Obesity is well known to cause raised blood pressure, and researchers here identify a novel mechanism for this effect involving leptin signaling. Since leptin signaling does change with age, it will be interesting to see whether or not this mechanism also operates to a significant degree in the…
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