A growing body of evidence suggests that microglia in the brain are important in the progression of neurodegenerative conditions such as Alzheimer’s disease. Like the similar macrophages outside the brain, microglia can adopt packages of behavior known as polarizations. M1 is an aggressive, inflammatory polarization suited to hunting pathogens, while M2 is an anti-inflammatory, pro-regenerati…
Loss of Beneficial Microglial Function in Alzheimer's Disease
A growing body of evidence suggests that microglia in the brain are important in the progression of neurodegenerative conditions such as Alzheimer’s disease. Like the similar macrophages outside the brain, microglia can adopt packages of behavior known as polarizations. M1 is an aggressive, inflammatory polarization suited to hunting pathogens, while M2 is an anti-inflammatory, pro-regenerati…