Microglial Autophagy in the Context of Neurodegenerative Conditions

Source https://www.fightaging.org/archives/2023/02/microglial-autophagy-in-the-context-of-neurodegenerative-conditions/

Changes in the function and activity of microglia in the brain, innate immune cells analogous to the macrophages present in the rest of the body, are known to be involved in the onset and progression of neurodegenerative conditions. Aging and neurodegeneration are associated with a growing presence of both senescent microglia and activated microglia Both of these states producing inflammatory signaling, contributing to the chronic, unresolved inflammation of brain tissue that is also characteristic of later life.

Autophagy is the name given to a c…

Source https://www.fightaging.org/archives/2023/02/microglial-autophagy-in-the-context-of-neurodegenerative-conditions/

Changes in the function and activity of microglia in the brain, innate immune cells analogous to the macrophages present in the rest of the body, are known to be involved in the onset and progression of neurodegenerative conditions. Aging and neurodegeneration are associated with a growing presence of both senescent microglia and activated microglia Both of these states producing inflammatory signaling, contributing to the chronic, unresolved inflammation of brain tissue that is also characteristic of later life.

Autophagy is the name given to a c…

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