On the Aging Adaptive Immune System

Source https://www.fightaging.org/archives/2021/02/on-the-aging-adaptive-immune-system/

An interesting fact about the adaptive immune system: the number of T cells in the body remains much the same across the entire lifespan, even after the supply of new T cells all but ceases in middle age. T cells are created as thymocytes by hematopoietic cells in the bone marrow, and then mature in the thymus. The supply of new cells from the bone marrow is negatively affected by age, while the thymus atrophies, active tissue becoming replaced with fat. Lacking replacements, the T cell population in the body becomes increasingly <a href="https://www.fightaging.org/archives/2017/08/senescent-t-cells-immunosenescence-and-t-cell-exhaustion-are-all-distinct-but-to-some-degree-overlapping-phenomena/…

Source https://www.fightaging.org/archives/2021/02/on-the-aging-adaptive-immune-system/

An interesting fact about the adaptive immune system: the number of T cells in the body remains much the same across the entire lifespan, even after the supply of new T cells all but ceases in middle age. T cells are created as thymocytes by hematopoietic cells in the bone marrow, and then mature in the thymus. The supply of new cells from the bone marrow is negatively affected by age, while the thymus atrophies, active tissue becoming replaced with fat. Lacking replacements, the T cell population in the body becomes increasingly <a href="https://www.fightaging.org/archives/2017/08/senescent-t-cells-immunosenescence-and-t-cell-exhaustion-are-all-distinct-but-to-some-degree-overlapping-phenomena/…

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