Atherosclerosis is the growth of fatty plaques in blood vessel walls, eventually growing to the point of narrowing vessels to reduce blood flow. Rupture of a plaque can cause a downstream blockage, and this is the cause of heart attack and stroke. As a result, atherosclerosis is the largest cause of human mortality. This remains the case even today because present approaches to the treatment of atherosclerosis do not reliably produce any sizable reduction in plaque size, and are very slow to remove enough plaque lipids to reduce risk of rupture by stabilizing the plaque structure. Available approaches have near entirely focused on reducing inflammation and lowering the <a href="https://doi.org/10.11…
Relationships Between Atherosclerosis and Other Age-Related Conditions
Atherosclerosis is the growth of fatty plaques in blood vessel walls, eventually growing to the point of narrowing vessels to reduce blood flow. Rupture of a plaque can cause a downstream blockage, and this is the cause of heart attack and stroke. As a result, atherosclerosis is the largest cause of human mortality. This remains the case even today because present approaches to the treatment of atherosclerosis do not reliably produce any sizable reduction in plaque size, and are very slow to remove enough plaque lipids to reduce risk of rupture by stabilizing the plaque structure. Available approaches have near entirely focused on reducing inflammation and lowering the <a href="https://doi.org/10.11…