Senescent Cells Inhibit Muscle Stem Cell Function and Regenerative Capacity

Source https://www.fightaging.org/archives/2022/12/senescent-cells-inhibit-muscle-stem-cell-function-and-regenerative-capacity/

Researchers here report on evidence for senescent cells in the stem cell niches supporting muscle tissue to reduce stem cell function and the capacity for muscle regeneration. Senescent cells accumulate with age throughout the body, and their inflammatory secretions are disruptive to tissue function. The development of many varied approaches to selectively destroy these errant cells is well underway in the biotech community, with the hope that late life health will be greatly improved as a result.

Tissue regeneration requires coordination between resident stem cells and l…

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