Soluable α-klotho Reduces Cardiac Fibrosis in Mice

Source https://www.fightaging.org/archives/2020/04/soluable-%CE%B1-klotho-reduces-cardiac-fibrosis-in-mice/

Klotho is a longevity-related gene. In mice, greater expression extends life while reduced expression shortens life. Most study has focused on beneficial effects on cognition and kidney function, with some debate over where in the body it acts – it may be that benefits to brain function are entirely the consequence of improved kidney function. That isn’t all that klotho does, however. The delivery of soluble α-klotho has emerged as a basis for building therapies based on klotho biochemistry, and Unity…