Sustained Midlife Weight Loss in Overweight Individuals Correlates with Reduced Incidence of Later Age-Related Disease

Source https://www.fightaging.org/archives/2025/06/sustained-midlife-weight-loss-in-overweight-individuals-correlates-with-reduced-incidence-of-later-age-related-disease/

An extensive literature of epidemiology demonstrates that being overweight correlates with increased age-related disease, increased medical expenditure, and increased mortality. The greater the excess weight, the worse the outcome. While human studies can largely only uncover correlations between lifestyle choice and health, animals studies convincingly demonstrate that carrying too much visceral fat is disruptive to health and life span. Visceral fat tissue is metabolically active, <a href="https://www.fightaging.org/archives/2013/03/a-mechanism-by-which-fat-causes-chronic-in…

Source https://www.fightaging.org/archives/2025/06/sustained-midlife-weight-loss-in-overweight-individuals-correlates-with-reduced-incidence-of-later-age-related-disease/

An extensive literature of epidemiology demonstrates that being overweight correlates with increased age-related disease, increased medical expenditure, and increased mortality. The greater the excess weight, the worse the outcome. While human studies can largely only uncover correlations between lifestyle choice and health, animals studies convincingly demonstrate that carrying too much visceral fat is disruptive to health and life span. Visceral fat tissue is metabolically active, <a href="https://www.fightaging.org/archives/2013/03/a-mechanism-by-which-fat-causes-chronic-in…

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