Source https://www.fightaging.org/archives/2021/08/the-age-related-decline-of-mitophagy-as-a-contributing-cause-of-stem-cell-dysfunction/
Stem cells support the maintenance of tissue by delivering a regular supply of daughter somatic cells to replace losses. Different tissues turn over at different rates, but the contribution of stem cells is vital. Stem cell function declines with age, however, and a slow spiral into frailty and organ failure follows as a consequence. In the most studied populations, this loss of stem cell function is largely a matter of declining activity in response to the age-damaged environment. Put into a youthful environment, stem cells from old tissues can still perform well.
Researchers here draw a line between declining mitophagy and declining stem cell function. Mitophagy is the specialized form of <a hre…
Source https://www.fightaging.org/archives/2021/08/the-age-related-decline-of-mitophagy-as-a-contributing-cause-of-stem-cell-dysfunction/
Stem cells support the maintenance of tissue by delivering a regular supply of daughter somatic cells to replace losses. Different tissues turn over at different rates, but the contribution of stem cells is vital. Stem cell function declines with age, however, and a slow spiral into frailty and organ failure follows as a consequence. In the most studied populations, this loss of stem cell function is largely a matter of declining activity in response to the age-damaged environment. Put into a youthful environment, stem cells from old tissues can still perform well.
Researchers here draw a line between declining mitophagy and declining stem cell function. Mitophagy is the specialized form of <a hre…
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