Source https://www.fightaging.org/archives/2024/07/the-gene-expression-patterns-of-inflammaging-and-immunosenescence-in-cynomolgus-macaques/
The aging of the immune system is an important contribution to frailty and age-related disease. Firstly the immune system becomes overactive, reacting to forms of the molecular damage of aging as though they were cancer, injury, or infection. Pathways evolved to be protective in youth instead become maladaptive in the damaged environment of aged tissue. The resulting constant inflammatory signaling is itself disruptive to tissue structure and function. This state is known as inflammaging.
Secondly, the immune system becomes progressively less able to coordinate its activities in order to attack and destroy <a href="ht…
Source https://www.fightaging.org/archives/2024/07/the-gene-expression-patterns-of-inflammaging-and-immunosenescence-in-cynomolgus-macaques/
The aging of the immune system is an important contribution to frailty and age-related disease. Firstly the immune system becomes overactive, reacting to forms of the molecular damage of aging as though they were cancer, injury, or infection. Pathways evolved to be protective in youth instead become maladaptive in the damaged environment of aged tissue. The resulting constant inflammatory signaling is itself disruptive to tissue structure and function. This state is known as inflammaging.
Secondly, the immune system becomes progressively less able to coordinate its activities in order to attack and destroy <a href="ht…
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