Treadmill Training for Old Mice Upregulates Autophagy and Improves Heart Function

Source https://www.fightaging.org/archives/2021/10/treadmill-training-for-old-mice-upregulates-autophagy-and-improves-heart-function/

It is well demonstrated that structured exercise programs improve function and reduce mortality in old humans, in part because the majority of people do not undertake anywhere near enough exercise. For mice, more activity takes place into later life, but how much is quite dependent on the environment in which they are housed. Looking at the study here, I would expect this to be a comparison of exercise trained mice with untrained mice that are less active than they would be if given options such as an exercise wheel. That may be a better match to the human situation than the other options. While looking at the results, it is worth recalling that past data shows that <a href="https://www.fightaging.org/archives/2013/10/exer…

Source https://www.fightaging.org/archives/2021/10/treadmill-training-for-old-mice-upregulates-autophagy-and-improves-heart-function/

It is well demonstrated that structured exercise programs improve function and reduce mortality in old humans, in part because the majority of people do not undertake anywhere near enough exercise. For mice, more activity takes place into later life, but how much is quite dependent on the environment in which they are housed. Looking at the study here, I would expect this to be a comparison of exercise trained mice with untrained mice that are less active than they would be if given options such as an exercise wheel. That may be a better match to the human situation than the other options. While looking at the results, it is worth recalling that past data shows that <a href="https://www.fightaging.org/archives/2013/10/exer…

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