Upregulation of Cyclophilin A as a Potential Path to Improve Aged Hematopoietic Stem Cell Function

Source https://www.fightaging.org/archives/2024/05/upregulation-of-cyclophilin-a-as-a-potential-path-to-improve-aged-hematopoietic-stem-cell-function/

Researchers here report on the importance of molecular chaperones, and cyclophilin A in particular, to the function of hematopoietic stem cells. These cells generate red blood cells and immune cells, and thus age-related changes in hematopoietic function have important consequences for health. The immune system runs awry with age, and altered hematopoiesis is one of the contributing factors. If, as researchers here suggest, upregulation of cyclophilin A can improve hematopoietic stem cell function, then using this as a basis for therapy may produce health benefits in older individuals.

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Source https://www.fightaging.org/archives/2024/05/upregulation-of-cyclophilin-a-as-a-potential-path-to-improve-aged-hematopoietic-stem-cell-function/

Researchers here report on the importance of molecular chaperones, and cyclophilin A in particular, to the function of hematopoietic stem cells. These cells generate red blood cells and immune cells, and thus age-related changes in hematopoietic function have important consequences for health. The immune system runs awry with age, and altered hematopoiesis is one of the contributing factors. If, as researchers here suggest, upregulation of cyclophilin A can improve hematopoietic stem cell function, then using this as a basis for therapy may produce health benefits in older individuals.

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