Inflammation and Cellular Senescence in the Aging Lung

Source https://www.fightaging.org/archives/2022/08/inflammation-and-cellular-senescence-in-the-aging-lung/

Here, researchers discuss what is known of the role of senescent cells, and the chronic inflammation that they create, in the aging of the lung. The first human trials of senolytic therapies to selectively destroy senescent cells were aimed at reversal of idiopathic pulmonary fibrosis. There is a good evidence for the growing presence of senescent cells to disrupt tissue maintenance and produce fibrosis as a result, the deposition of excessive, scar-like c…