An Update on Revel Pharmaceuticals, Working on Glucosepane Cross Link Breakers

Source https://www.fightaging.org/archives/2021/10/an-update-on-revel-pharmaceuticals-working-on-glucosepane-cross-link-breakers/

Revel Pharmaceuticals is the result of work funded in large part by the SENS Research Foundation, with the support of its many philanthropic donors. That part of the history of the underlying research isn’t covered in today’s short article on the company, so it seems worth mentioning here. Cross-links are chemical bonds formed between molecules in the extracellular matrix. Some are necessary to structure and function, but other unwanted cross-links are added over the years, creating stiffness in flexible tissues such as blood vessel walls and skin. In the case of blood vessels, <a href="https://www.fightaging.org/archives/2014/05/arterial-stiffening-is-enough-to-explain-h…

Source https://www.fightaging.org/archives/2021/10/an-update-on-revel-pharmaceuticals-working-on-glucosepane-cross-link-breakers/

Revel Pharmaceuticals is the result of work funded in large part by the SENS Research Foundation, with the support of its many philanthropic donors. That part of the history of the underlying research isn’t covered in today’s short article on the company, so it seems worth mentioning here. Cross-links are chemical bonds formed between molecules in the extracellular matrix. Some are necessary to structure and function, but other unwanted cross-links are added over the years, creating stiffness in flexible tissues such as blood vessel walls and skin. In the case of blood vessels, <a href="https://www.fightaging.org/archives/2014/05/arterial-stiffening-is-enough-to-explain-h…

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