Fight Aging! Newsletter, March 25th 2024

Source https://www.fightaging.org/archives/2024/03/fight-aging-newsletter-march-25th-2024/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/


Contents

Source https://www.fightaging.org/archives/2024/03/fight-aging-newsletter-march-25th-2024/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/


Contents

Thoughts on What is Revealed in the Trial Data for Amyloid-β Clearance

Source https://www.fightaging.org/archives/2024/03/thoughts-on-what-is-revealed-in-the-trial-data-for-amyloid-%CE%B2-clearance/

There are now several immunotherapies capable of clearing amyloid-β aggregates from the aging brain, and a sizable amount of clinical trial data to look through. Sadly, this approach doesn’t much help patients in the later stages of Alzheimer’s disease, but the evidence to date suggests that it may be useful in prevention if the clearance is conducted early enough. Amyloid-β aggregation causes mild cognitive impairment in and of itself, but really just sets the stage for a set of different processes, inflammation and <a href="https://en.wikipedia.org/wiki/Neurofi…

Source https://www.fightaging.org/archives/2024/03/thoughts-on-what-is-revealed-in-the-trial-data-for-amyloid-%CE%B2-clearance/

There are now several immunotherapies capable of clearing amyloid-β aggregates from the aging brain, and a sizable amount of clinical trial data to look through. Sadly, this approach doesn’t much help patients in the later stages of Alzheimer’s disease, but the evidence to date suggests that it may be useful in prevention if the clearance is conducted early enough. Amyloid-β aggregation causes mild cognitive impairment in and of itself, but really just sets the stage for a set of different processes, inflammation and <a href="https://en.wikipedia.org/wiki/Neurofi…

How to Let Go of the Past and Forgive

Source https://tinybuddha.com/blog/how-to-let-go-of-the-past-and-forgive/

“Forgive others not because they deserve forgiveness, but because you deserve peace.” ~Jonathan Lockwood Huie

As a child, I faced constant physical and mental abuse.

Several classmates would beat me up in the schoolyard, hitting and kicking me. They also chased me down the streets to my home when school was done for the day. I had to cycle at my fastest to avoid another beating. It felt like I had to go through a war zone every day.

Besides the physical abuse, these children also constantly criticized and ridiculed every single thing I did. This made me feel incredibly insecure about a lot of…

Source https://tinybuddha.com/blog/how-to-let-go-of-the-past-and-forgive/

“Forgive others not because they deserve forgiveness, but because you deserve peace.” ~Jonathan Lockwood Huie

As a child, I faced constant physical and mental abuse.

Several classmates would beat me up in the schoolyard, hitting and kicking me. They also chased me down the streets to my home when school was done for the day. I had to cycle at my fastest to avoid another beating. It felt like I had to go through a war zone every day.

Besides the physical abuse, these children also constantly criticized and ridiculed every single thing I did. This made me feel incredibly insecure about a lot of…

Voting 2024 – Links to Help

Source https://seniorplanet.org/articles-voting-2024-links/

Voting in 2024 starts with voter registration and state primaries with varying requirements and deadlines. These links can help.

The post Voting 2024 – Links to Help appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-voting-2024-links/

Voting in 2024 starts with voter registration and state primaries with varying requirements and deadlines. These links can help.

The post Voting 2024 – Links to Help appeared first on Senior Planet from AARP.

William, 66 – No Limits!

Source https://seniorplanet.org/articles-sa-william-66-no-limits/

After receiving a serious diagnosis from his doctor, Senior Planet Sponsored Athlete William Lee rekindled a passion for fitness that had been dormant since his days in the Army.

The post William, 66 – No Limits! appeared first on Senior Planet from AARP.

Source https://seniorplanet.org/articles-sa-william-66-no-limits/

After receiving a serious diagnosis from his doctor, Senior Planet Sponsored Athlete William Lee rekindled a passion for fitness that had been dormant since his days in the Army.

The post William, 66 – No Limits! appeared first on Senior Planet from AARP.

How I Broke Free from Burnout by Eating More

Source https://tinybuddha.com/blog/how-i-broke-free-from-burnout-by-eating-more/

“Our food should be our medicine, and our medicine should be our food.” ~Hippocrates

There I was—it was 3 p.m. on my first day at my new job, the job I was so desperate for, and I was falling asleep. Right there, in a conference room filled with over twenty people, and I was nodding off.

I couldn’t believe it. I was embarrassed, ashamed, and seriously questioning if I was ready or capable of this whole “adult” thing. How was it that I could barely keep my eyes open on my first day? I was supposed to be a young, vibrant, twenty-three-year-old woman taking on the world.

And I fell asleep.

I had heard about burnout. Sur…

Source https://tinybuddha.com/blog/how-i-broke-free-from-burnout-by-eating-more/

“Our food should be our medicine, and our medicine should be our food.” ~Hippocrates

There I was—it was 3 p.m. on my first day at my new job, the job I was so desperate for, and I was falling asleep. Right there, in a conference room filled with over twenty people, and I was nodding off.

I couldn’t believe it. I was embarrassed, ashamed, and seriously questioning if I was ready or capable of this whole “adult” thing. How was it that I could barely keep my eyes open on my first day? I was supposed to be a young, vibrant, twenty-three-year-old woman taking on the world.

And I fell asleep.

I had heard about burnout. Sur…

How to Break Dependence on the Phone

Source https://zenhabits.net/break-phone-dependence/

By Leo Babauta

On average, people spend more than 3 hours on their phones each day, picking up their phones nearly 60 times a day … with some people spending closer to 4 hours.

These numbers aren’t meant to be judgments — it’s not a bad thing to look at your phone — but instead are meant to bring some awareness to our phone usage.

A lot of people I talk to want to decrease their usage of phones — not necessarily decreasing to zero, but decreasing impulsive usage of their phones.

Many of us tend to grab our phones anytime there’s a lull, and once you get on your phone it can lead to mindless scrolling.

So how can we develop more mindful use of our phones, and become less dependent on them?

Let’s explore together.

Becoming More Mindful of Phone Usage

If you don’t have awareness, you can’t change something. …

Source https://zenhabits.net/break-phone-dependence/

By Leo Babauta

On average, people spend more than 3 hours on their phones each day, picking up their phones nearly 60 times a day … with some people spending closer to 4 hours.

These numbers aren’t meant to be judgments — it’s not a bad thing to look at your phone — but instead are meant to bring some awareness to our phone usage.

A lot of people I talk to want to decrease their usage of phones — not necessarily decreasing to zero, but decreasing impulsive usage of their phones.

Many of us tend to grab our phones anytime there’s a lull, and once you get on your phone it can lead to mindless scrolling.

So how can we develop more mindful use of our phones, and become less dependent on them?

Let’s explore together.

Becoming More Mindful of Phone Usage

If you don’t have awareness, you can’t change something. …

Human Exosomes Harvested from Stem Cells in Urine Produce Rejuvenation in Mice

Source https://www.fightaging.org/archives/2024/03/human-exosomes-harvested-from-stem-cells-in-urine-produce-rejuvenation-in-mice/

Exosomes are a class of extracellular vesicle, membrane-wrapped packages of molecules that carry a sizable fraction of the chemical communications that takes place between cells. The various types of extracellular vesicle are presently ordered in a taxonomy by their size rather than any more subtle combination of features. Those subtle features definitely exist; exosomes from different cell types and different environmental circumstances are quite different from one another in any number of ways. The present taxonomy of extracellular vesicles is indicative of a lack of detailed understanding regarding (a) the mechanisms determining formation of extracellular vesicles, as well as (b) the factors determining the contents of extracellular vesicles.

The stem cell therapies t…

Source https://www.fightaging.org/archives/2024/03/human-exosomes-harvested-from-stem-cells-in-urine-produce-rejuvenation-in-mice/

Exosomes are a class of extracellular vesicle, membrane-wrapped packages of molecules that carry a sizable fraction of the chemical communications that takes place between cells. The various types of extracellular vesicle are presently ordered in a taxonomy by their size rather than any more subtle combination of features. Those subtle features definitely exist; exosomes from different cell types and different environmental circumstances are quite different from one another in any number of ways. The present taxonomy of extracellular vesicles is indicative of a lack of detailed understanding regarding (a) the mechanisms determining formation of extracellular vesicles, as well as (b) the factors determining the contents of extracellular vesicles.

The stem cell therapies t…

How to Recognize a Toxic Relationship and Know When It’s Time to Leave

Source https://tinybuddha.com/blog/how-to-recognize-a-toxic-relationship-and-know-when-its-time-to-leave/

“Your heart knows the way. Run in that direction.” ~Rumi

Have you ever found yourself questioning the health of your relationship, unsure if what you’re experiencing is normal or if it’s veering into toxic territory? It’s a common dilemma that many of us face at some point in our lives.

But how do we know when it’s time to walk away?

Toxic relationships can be insidious, often starting out innocently enough before gradually morphing into something destructive and harmful. The warning signs may be subtle at first, but they can become impossible to ignore over time.

Flashback to …

Source https://tinybuddha.com/blog/how-to-recognize-a-toxic-relationship-and-know-when-its-time-to-leave/

“Your heart knows the way. Run in that direction.” ~Rumi

Have you ever found yourself questioning the health of your relationship, unsure if what you’re experiencing is normal or if it’s veering into toxic territory? It’s a common dilemma that many of us face at some point in our lives.

But how do we know when it’s time to walk away?

Toxic relationships can be insidious, often starting out innocently enough before gradually morphing into something destructive and harmful. The warning signs may be subtle at first, but they can become impossible to ignore over time.

Flashback to …

Your List of the Best and Protective Hairstyles for Alopecia

Source https://greatist.com/health/best-protective-hairstyles-alopecia

If patches of hair loss are messing with your self-image, a different do could be the way to hide them — and protect the hair you still have.

Hair falls out for lots of different reasons — you’re getting older, you don’t eat enough nutrients, or you’re overdoing it on the heat styling.

Sometimes a condition like alopecia areata makes you lose your hair. If you think of your hair as an integral part of your identity, seeing missing patches when you look in the mirror can be distressing, to say the least.

There’s a chance your hair will eventually grow back on its own. If it doesn’t, or it’s growing at a snail’s pace, your dermatologist has treatments to bring it back faster. 

In the meantime, a few clever styling tricks can masquerade those bald spots and …

Source https://greatist.com/health/best-protective-hairstyles-alopecia

If patches of hair loss are messing with your self-image, a different do could be the way to hide them — and protect the hair you still have.

Hair falls out for lots of different reasons — you’re getting older, you don’t eat enough nutrients, or you’re overdoing it on the heat styling.

Sometimes a condition like alopecia areata makes you lose your hair. If you think of your hair as an integral part of your identity, seeing missing patches when you look in the mirror can be distressing, to say the least.

There’s a chance your hair will eventually grow back on its own. If it doesn’t, or it’s growing at a snail’s pace, your dermatologist has treatments to bring it back faster. 

In the meantime, a few clever styling tricks can masquerade those bald spots and …

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