Calorie Restriction versus the Aging of Microglia

Source https://www.fightaging.org/archives/2020/05/calorie-restriction-versus-the-aging-of-microglia/

Microglia are immune cells of the brain, analogous to macrophages in the rest of the body. They take on a broad range of tasks: chasing down pathogens; clearing up cell debris and molecular waste; assisting in regeneration and tissue maintenance; assisting neurons in remodeling of synapses. Microglia, like macrophages, can shift between behavior patterns in response to environmental circumstances, such as M1 (inflammatory and aggressive) and M2 (anti-inflammatory and regenerative).

With advancing age, microglia become increasingly inflammatory:…

Source https://www.fightaging.org/archives/2020/05/calorie-restriction-versus-the-aging-of-microglia/

Microglia are immune cells of the brain, analogous to macrophages in the rest of the body. They take on a broad range of tasks: chasing down pathogens; clearing up cell debris and molecular waste; assisting in regeneration and tissue maintenance; assisting neurons in remodeling of synapses. Microglia, like macrophages, can shift between behavior patterns in response to environmental circumstances, such as M1 (inflammatory and aggressive) and M2 (anti-inflammatory and regenerative).

With advancing age, microglia become increasingly inflammatory:…

Mindstrong Health raises $100M to transform how we measure and promote mental health

Source: https://sharpbrains.com/blog/2020/05/26/mindstrong-health-raises-100m-to-transform-how-we-measure-and-promote-mental-health/

Mindstrong scores $100M to monitor wellness via smartphone behaviors (MobiHealth News):

This morning digital mental health platform Mindstrong scored a whopping $100 million in Series C funding.

While Mindstrong has a history of solid funding rounds, this amount will more than double its total funding. In 2017 it got its first $14 million cash infusion. That was followed by a $15 million Series B funding round in June of 2018, which got a $31 million add-on in January of 2019, bringing the company’s total funding to just under $60 million before this news.

The company was first founded in 2014, but it made a splash in 2017 when forme…

Source: https://sharpbrains.com/blog/2020/05/26/mindstrong-health-raises-100m-to-transform-how-we-measure-and-promote-mental-health/

Mindstrong scores $100M to monitor wellness via smartphone behaviors (MobiHealth News):

This morning digital mental health platform Mindstrong scored a whopping $100 million in Series C funding.

While Mindstrong has a history of solid funding rounds, this amount will more than double its total funding. In 2017 it got its first $14 million cash infusion. That was followed by a $15 million Series B funding round in June of 2018, which got a $31 million add-on in January of 2019, bringing the company’s total funding to just under $60 million before this news.

The company was first founded in 2014, but it made a splash in 2017 when forme…

Bear It In Mind – LIFELONG IMPACTS OF PREGNANCY ON A WOMAN’S BRAIN

Source: https://womensbrainhealth.org/better-thinking/bear-it-in-mind-lifelong-impacts-of-pregnancy-on-a-womans-brain

by Women’s Brain Health Initiative: Women are disproportionately affected by many brain disorders. For example, it is estimated that almost 70% of individuals diagnosed with Alzheimer’s disease are women. Women’s Brain Health Initiative and the Brain Canada Foundation have been……

Source: https://womensbrainhealth.org/better-thinking/bear-it-in-mind-lifelong-impacts-of-pregnancy-on-a-womans-brain

by Women’s Brain Health Initiative: Women are disproportionately affected by many brain disorders. For example, it is estimated that almost 70% of individuals diagnosed with Alzheimer’s disease are women. Women’s Brain Health Initiative and the Brain Canada Foundation have been……

Why Joy Is Important for Healing Developmental Trauma

Source http://feedproxy.google.com/~r/tinybuddha/~3/-877Lok3qSs/

“We all have everything we need within us to create our fullest potential.” ~Abraham Maslow

Did you grow up with a critical, distant, or ignorant mother?

She probably made sure that your physical needs were covered, but she never noticed or understood your emotional needs. If she was anything like my mum, she may even have shamed you for having them!

You’re an adult now, and you have everything you need to be happy. So why aren’t you? Instead, you feel unworthy, disconnected, and lonely even when you’re with people you love. There’s this constant emptiness inside that makes you angry and sad at the same time.<span lang="EN-GB…

Source http://feedproxy.google.com/~r/tinybuddha/~3/-877Lok3qSs/

“We all have everything we need within us to create our fullest potential.” ~Abraham Maslow

Did you grow up with a critical, distant, or ignorant mother?

She probably made sure that your physical needs were covered, but she never noticed or understood your emotional needs. If she was anything like my mum, she may even have shamed you for having them!

You’re an adult now, and you have everything you need to be happy. So why aren’t you? Instead, you feel unworthy, disconnected, and lonely even when you’re with people you love. There’s this constant emptiness inside that makes you angry and sad at the same time.<span lang="EN-GB…

Quarantine Shines a Light on the Health Effects of Loneliness & Social Isolation

Source: https://womensbrainhealth.org/think-about-it/quarantine-shines-a-light-on-the-health-effects-of-loneliness-social-isolation

by Vicky Leavitt for Daily Grit: As a cognitive neuroscientist and clinical neuropsychologist, I have been yammering away for years about the detrimental effects of loneliness and social isolation on brain health and overall health. Loneliness and social isolation have long been of interest to……

Source: https://womensbrainhealth.org/think-about-it/quarantine-shines-a-light-on-the-health-effects-of-loneliness-social-isolation

by Vicky Leavitt for Daily Grit: As a cognitive neuroscientist and clinical neuropsychologist, I have been yammering away for years about the detrimental effects of loneliness and social isolation on brain health and overall health. Loneliness and social isolation have long been of interest to……

Could a Hormone Help Spur High Blood Pressure?

Source: https://www.webmd.com/hypertension-high-blood-pressure/news/20200526/could-a-hormone-help-spur-high-blood-pressure?src=RSS_PUBLIC

650x350_listicle_foods_to_avoid_high_blood_pressur

Many people with high blood pressure may have an unrecognized hormonal condition driving their numbers up, a new study suggests.

Source: https://www.webmd.com/hypertension-high-blood-pressure/news/20200526/could-a-hormone-help-spur-high-blood-pressure?src=RSS_PUBLIC

650x350_listicle_foods_to_avoid_high_blood_pressur

Many people with high blood pressure may have an unrecognized hormonal condition driving their numbers up, a new study suggests.

Vaccination as a Limited Option for Removal of Senescent Cells

Source https://www.fightaging.org/archives/2020/05/vaccination-as-a-limited-option-for-removal-of-senescent-cells/

In today’s open access paper, the authors demonstrate a form of vaccination against a surface marker that appears on a subset of senescent T cells that reside in fat tissue, thus directing the rest of the immune system to attack and destroy these cells. There is good evidence for excess fat tissue to result in an increased burden of senescent cells, which disrupt metabolism via the generation of inflammatory signals. A novel branch of medicine is under construction, based on <a href="https://www.fightaging.org/archives/2017/09/senolytic-therapies-to-clear-senescent-cells-will-transform-the-fiel…

Source https://www.fightaging.org/archives/2020/05/vaccination-as-a-limited-option-for-removal-of-senescent-cells/

In today’s open access paper, the authors demonstrate a form of vaccination against a surface marker that appears on a subset of senescent T cells that reside in fat tissue, thus directing the rest of the immune system to attack and destroy these cells. There is good evidence for excess fat tissue to result in an increased burden of senescent cells, which disrupt metabolism via the generation of inflammatory signals. A novel branch of medicine is under construction, based on <a href="https://www.fightaging.org/archives/2017/09/senolytic-therapies-to-clear-senescent-cells-will-transform-the-fiel…

Placentas from COVID-19-positive pregnant women show injury

Source: http://www.brainhealtheducation.org/placentas-from-covid-19-positive-pregnant-women-show-injury/

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study. The type of injury seen in the placentas shows abnormal blood flow between the mothers and their babies in utero, pointing to a new complication of

Read More…

Source: http://www.brainhealtheducation.org/placentas-from-covid-19-positive-pregnant-women-show-injury/

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study. The type of injury seen in the placentas shows abnormal blood flow between the mothers and their babies in utero, pointing to a new complication of

Read More…

Exercise improves memory and boosts blood flow to brain

Source: http://www.brainhealtheducation.org/exercise-improves-memory-and-boosts-blood-flow-to-brain/

Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory. But what happens during exercise to trigger these benefits? New UT Southwestern research that mapped brain changes after one year of aerobic workouts has uncovered a potentially critical process: Exercise boosts blood flow into two

Read More…

Source: http://www.brainhealtheducation.org/exercise-improves-memory-and-boosts-blood-flow-to-brain/

Scientists have collected plenty of evidence linking exercise to brain health, with some research suggesting fitness may even improve memory. But what happens during exercise to trigger these benefits? New UT Southwestern research that mapped brain changes after one year of aerobic workouts has uncovered a potentially critical process: Exercise boosts blood flow into two

Read More…

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