Source https://www.fightaging.org/archives/2022/03/fight-aging-newsletter-march-21st-2022/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
- Elastin Fragmentation and the Elastin Receptor Complex in Aging Blood Vessels
- Mitochondrial DNA Mu…
Source https://www.fightaging.org/archives/2022/03/fight-aging-newsletter-march-21st-2022/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
- Elastin Fragmentation and the Elastin Receptor Complex in Aging Blood Vessels
- Mitochondrial DNA Mu…
Source https://www.fightaging.org/archives/2022/03/the-interaction-between-metabolism-and-stem-cell-aging/
In today’s open access paper, researchers discuss the influence of metabolism on the aging of stem cells. Stem cells maintain tissue by providing a supply of daughter somatic cells to replace losses. Animals have evolved to minimize the risk of cancer by limiting the ability of near all cells to replicate. Somatic cells operate under the Hayflick limit, driven by loss of telomere length with each cell division, leading to senescence or self-destruction when telomeres are short. Stem cells use telomerase to maintain long telomeres and thus continually produce replacement somatic cells with long telomeres.
Unfortunately <a href="https://ww…
Source https://www.fightaging.org/archives/2022/03/the-interaction-between-metabolism-and-stem-cell-aging/
In today’s open access paper, researchers discuss the influence of metabolism on the aging of stem cells. Stem cells maintain tissue by providing a supply of daughter somatic cells to replace losses. Animals have evolved to minimize the risk of cancer by limiting the ability of near all cells to replicate. Somatic cells operate under the Hayflick limit, driven by loss of telomere length with each cell division, leading to senescence or self-destruction when telomeres are short. Stem cells use telomerase to maintain long telomeres and thus continually produce replacement somatic cells with long telomeres.
Unfortunately <a href="https://ww…
Source https://seniorplanet.org/ask-the-techspert-what-is-a-vpn/
Learn what a VPN can do to protect your internet connection and enhance your online privacy.
The post Ask The Techspert: What is a VPN? appeared first on Senior Planet.
…
Source https://seniorplanet.org/ask-the-techspert-what-is-a-vpn/
Learn what a VPN can do to protect your internet connection and enhance your online privacy.
The post Ask The Techspert: What is a VPN? appeared first on Senior Planet.
…
Source https://www.fightaging.org/archives/2022/03/physical-activity-improves-brain-function-in-later-life/
Many studies of exercise and health support the view that older people typically undertake far less exercise than they should. Exercise improves function and lowers mortality risk, and therefore the less active segment of the older population are only harming themselves. We evolved to be active throughout life, and we suffer when that is not the case. As researchers note here, the dose-response curve for exercise results in sizable benefits when moving from little exercise to some exercise, and diminishing returns with further increases. Evidence suggests that the optimal level is probably still somewhat more than the established 150 minutes p…
Source https://www.fightaging.org/archives/2022/03/physical-activity-improves-brain-function-in-later-life/
Many studies of exercise and health support the view that older people typically undertake far less exercise than they should. Exercise improves function and lowers mortality risk, and therefore the less active segment of the older population are only harming themselves. We evolved to be active throughout life, and we suffer when that is not the case. As researchers note here, the dose-response curve for exercise results in sizable benefits when moving from little exercise to some exercise, and diminishing returns with further increases. Evidence suggests that the optimal level is probably still somewhat more than the established 150 minutes p…
Source https://www.fightaging.org/archives/2022/03/the-role-of-mitochondrial-dna-mutation-in-aging-remains-much-debated/
Mitochondria are the power plants of the cell, deeply integrated into many core cellular processes, but most importantly, responsible for generating the energy store molecule adenosine triphosphate (ATP), used to power cellular processes. Mitochondria are descended from ancient symbiotic bacteria, and act like bacteria in many ways, fusing and dividing, and passing around component parts promiscuously. Every cell contains a herd of hundreds of these organelles, monitored by quality control processes that destroy worn mitochondria in order to maintain overall function.
Importantly, mitochondria contain their own small circular genome. Mitochondrial DNA is less well protected than t…
Source https://www.fightaging.org/archives/2022/03/the-role-of-mitochondrial-dna-mutation-in-aging-remains-much-debated/
Mitochondria are the power plants of the cell, deeply integrated into many core cellular processes, but most importantly, responsible for generating the energy store molecule adenosine triphosphate (ATP), used to power cellular processes. Mitochondria are descended from ancient symbiotic bacteria, and act like bacteria in many ways, fusing and dividing, and passing around component parts promiscuously. Every cell contains a herd of hundreds of these organelles, monitored by quality control processes that destroy worn mitochondria in order to maintain overall function.
Importantly, mitochondria contain their own small circular genome. Mitochondrial DNA is less well protected than t…
Source https://tinybuddha.com/blog/how-to-feel-comfortable-setting-boundaries-and-why-we-need-them/
“Avoiding certain people to protect your emotional health is not weakness. It is wisdom.” ~Unknown
The word “boundary” often conjures up negative thoughts. After all, it’s usually an indication of something being restricted.
However, deciding to set boundaries is one of the most empowering things you can do for your mental well-being.
Growing up I always put the needs of others before my own, and not much has changed in my adult life.
While I enjoy the idea of being a mediator in some ways, or the person that other people come to in times of need, it gets exhausting and emotionally draining.
You see, the more you engage in these sorts of dynamics the more dif…
Source https://tinybuddha.com/blog/how-to-feel-comfortable-setting-boundaries-and-why-we-need-them/
“Avoiding certain people to protect your emotional health is not weakness. It is wisdom.” ~Unknown
The word “boundary” often conjures up negative thoughts. After all, it’s usually an indication of something being restricted.
However, deciding to set boundaries is one of the most empowering things you can do for your mental well-being.
Growing up I always put the needs of others before my own, and not much has changed in my adult life.
While I enjoy the idea of being a mediator in some ways, or the person that other people come to in times of need, it gets exhausting and emotionally draining.
You see, the more you engage in these sorts of dynamics the more dif…
Source https://tinybuddha.com/blog/the-chaos-of-life-after-loss-and-the-love-that-never-dies/
“We need to grieve the ones we’ve lost—not to sustain our connection to suffering, but to sustain our connection to love.” ~Jennifer Williamson
Ken was only forty-seven years old when he met his untimely death.
It was surreal, my brother-in-law was gone from our physical world.
As a family, we felt the motions moving through the initial telephone call summoning us to the hospital to the time we surrounded him as he took his last breath. It was if we were all caught between two worlds, one of cruel reality and one of complete disbelief. You read about it happening to other people, not to us.
My chest felt like a dense, cold stone had been dropped abruptly on it aimed at my heart after hearing those words hit my ears: “He’s not going to make it̷…
Source https://tinybuddha.com/blog/the-chaos-of-life-after-loss-and-the-love-that-never-dies/
“We need to grieve the ones we’ve lost—not to sustain our connection to suffering, but to sustain our connection to love.” ~Jennifer Williamson
Ken was only forty-seven years old when he met his untimely death.
It was surreal, my brother-in-law was gone from our physical world.
As a family, we felt the motions moving through the initial telephone call summoning us to the hospital to the time we surrounded him as he took his last breath. It was if we were all caught between two worlds, one of cruel reality and one of complete disbelief. You read about it happening to other people, not to us.
My chest felt like a dense, cold stone had been dropped abruptly on it aimed at my heart after hearing those words hit my ears: “He’s not going to make it̷…
Source https://tinybuddha.com/blog/how-mindfulness-helped-me-become-my-own-best-friend/
“With mindfulness, you can establish yourself in the present in order to touch the wonders of life that are available in that moment.” ~Thich Nhat Hanh
I am not a good friend to myself. This realization shook me as I was riding the bus home one day from the local university where I taught.
This realization had been building for some time, but it struck me powerfully that day. I was teaching a summer class on Asian philosophy, and we were reading the Sayings of Buddha. We had been discussing a passage about a monk watching his feelings.
The passage explained that when the monk had happy feelings, he knew he had happy feelings. And when he had unhappy feelings, he knew he had unhappy feelings. And as the monk went about his day, the passage went on, he watched hi…
Source https://tinybuddha.com/blog/how-mindfulness-helped-me-become-my-own-best-friend/
“With mindfulness, you can establish yourself in the present in order to touch the wonders of life that are available in that moment.” ~Thich Nhat Hanh
I am not a good friend to myself. This realization shook me as I was riding the bus home one day from the local university where I taught.
This realization had been building for some time, but it struck me powerfully that day. I was teaching a summer class on Asian philosophy, and we were reading the Sayings of Buddha. We had been discussing a passage about a monk watching his feelings.
The passage explained that when the monk had happy feelings, he knew he had happy feelings. And when he had unhappy feelings, he knew he had unhappy feelings. And as the monk went about his day, the passage went on, he watched hi…
Source https://www.fightaging.org/archives/2022/03/variations-in-biological-age-across-organs-in-younger-individuals/
Systems of measuring biological age are multiplying rapidly. There are many ways of going about this, from epigenetic clocks to weighted combinations of simple measures such as grip strength. Researchers here build their own assessments for the purpose of looking at aging in younger adults, 20s to 40s, a part of aging that is not well studied at all. The interesting outcome is that there appears to be a significant variation in assessed biological age between different organs and systems in the body. It is a little early to talk about why this arises, whether an artifact of the tools used, or reflects some underlying truth about the nature of aging.
Investigators recruited 4,066 volunteers to supply blood and …
Source https://www.fightaging.org/archives/2022/03/variations-in-biological-age-across-organs-in-younger-individuals/
Systems of measuring biological age are multiplying rapidly. There are many ways of going about this, from epigenetic clocks to weighted combinations of simple measures such as grip strength. Researchers here build their own assessments for the purpose of looking at aging in younger adults, 20s to 40s, a part of aging that is not well studied at all. The interesting outcome is that there appears to be a significant variation in assessed biological age between different organs and systems in the body. It is a little early to talk about why this arises, whether an artifact of the tools used, or reflects some underlying truth about the nature of aging.
Investigators recruited 4,066 volunteers to supply blood and …
Source https://zenhabits.net/obsess/
Sometimes, our heads won’t stop thinking about something. Our thoughts will spin around and around, not willing to let go, obsessing. It might be about another person, a big event coming up, or about ourselves. It might be overthinking a decision, big or small.
There’s nothing wrong with this. It’s a human thing to do, to overthink or obsess about something we’re worried or frustrated about. It’s a sign that we’re feeling fear and uncertainty, and our brains are trying to solve it.
Sometimes, though, it can be liberating to let go of that kind of thinking. It can lead to better sleep, peace of mind, and a simplicity of living. So how can we do that?
I’ll share a process for that briefly here:
- Notice. Often when we’re caught up in a loop or overthinking, we aren’t aware of it. It seems like the right thing to do, to keep thinking about this th…
Source https://zenhabits.net/obsess/
Sometimes, our heads won’t stop thinking about something. Our thoughts will spin around and around, not willing to let go, obsessing. It might be about another person, a big event coming up, or about ourselves. It might be overthinking a decision, big or small.
There’s nothing wrong with this. It’s a human thing to do, to overthink or obsess about something we’re worried or frustrated about. It’s a sign that we’re feeling fear and uncertainty, and our brains are trying to solve it.
Sometimes, though, it can be liberating to let go of that kind of thinking. It can lead to better sleep, peace of mind, and a simplicity of living. So how can we do that?
I’ll share a process for that briefly here:
- Notice. Often when we’re caught up in a loop or overthinking, we aren’t aware of it. It seems like the right thing to do, to keep thinking about this th…