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A Caution Not to Forget the Continued Need for Fundamental Research into Aging

Source https://www.fightaging.org/archives/2022/02/a-caution-not-to-forget-the-continued-need-for-fundamental-research-into-aging/

A growing longevity industry is picking up ongoing academic projects in increasing numbers and working towards the clinical availability of therapies to treat aging. Amidst all the light and noise, one of the researchers in the field here asks for us not to overlook the need for more fundamental research. I agree, though I’d say that the most important portion of research not to be overlooked are the projects in the SENS rejuvenation biotechnology portfolio yet to make it to enthusiastic commercial development. To my eyes, the fastest way to find out more about how aging works is to implement and test specific rejuvenation strategies, each of which addresses only a narrow aspect of aging.

João Pedro de Magalhães has dedicated his career to understanding the biological puzzle of aging. W…

Source https://www.fightaging.org/archives/2022/02/a-caution-not-to-forget-the-continued-need-for-fundamental-research-into-aging/

A growing longevity industry is picking up ongoing academic projects in increasing numbers and working towards the clinical availability of therapies to treat aging. Amidst all the light and noise, one of the researchers in the field here asks for us not to overlook the need for more fundamental research. I agree, though I’d say that the most important portion of research not to be overlooked are the projects in the SENS rejuvenation biotechnology portfolio yet to make it to enthusiastic commercial development. To my eyes, the fastest way to find out more about how aging works is to implement and test specific rejuvenation strategies, each of which addresses only a narrow aspect of aging.

João Pedro de Magalhães has dedicated his career to understanding the biological puzzle of aging. W…

5 Important Life Skills I Learned in Grief After My Husband Died

Source https://tinybuddha.com/blog/5-important-life-skills-i-learned-in-grief-after-my-husband-died/

“Sit with it. Sit with it. Sit with it. Sit with it. Even though you want to run. Even when it’s heavy and difficult. Even though you’re not quite sure of the way through. Healing happens by feeling.” ~Dr. Rebecca Ray

When my husband died from terminal brain cancer in 2014, I learned all about deep grief. The kind of grief that plunges you into a valley of pain so vast it takes years to claw your way out. In the beginning, I didn’t want to deal with grief because the pain was too intense. So, I dodged grief and circled around the pit of despair, trying to outrun or outwit it.

My biggest grief fault was imagining an end. In my naiveté I figured I’d reach a point where I could wash my hands of it …

Source https://tinybuddha.com/blog/5-important-life-skills-i-learned-in-grief-after-my-husband-died/

“Sit with it. Sit with it. Sit with it. Sit with it. Even though you want to run. Even when it’s heavy and difficult. Even though you’re not quite sure of the way through. Healing happens by feeling.” ~Dr. Rebecca Ray

When my husband died from terminal brain cancer in 2014, I learned all about deep grief. The kind of grief that plunges you into a valley of pain so vast it takes years to claw your way out. In the beginning, I didn’t want to deal with grief because the pain was too intense. So, I dodged grief and circled around the pit of despair, trying to outrun or outwit it.

My biggest grief fault was imagining an end. In my naiveté I figured I’d reach a point where I could wash my hands of it …

Want to Change Your Life? Draw the “You” You Want to Be

Source https://tinybuddha.com/blog/want-to-change-your-life-draw-the-you-you-want-to-be/

“You are not too old and it is not too late.” ~Unknown

In less than a month, I’ll be hitting a major “milestone” birthday. I quit my full-time job six months ago, ending a twenty-plus year career in education, and have spent time thinking about what I want the next chapter of my life to look like. I found myself thinking back to a drawing exercise I did a few years ago that has made such an impact on my being willing to make major changes in my life.

Entering my mid-forties, I had come to a point where something just felt “off.” I wasn’t sleeping well, often waking at 3am with anxiety about real or imagined catastrophes. I was often stressed and short-tempered. I was gaining weight and my health wasn’t in the top-notch condition the way it had always bee…

Source https://tinybuddha.com/blog/want-to-change-your-life-draw-the-you-you-want-to-be/

“You are not too old and it is not too late.” ~Unknown

In less than a month, I’ll be hitting a major “milestone” birthday. I quit my full-time job six months ago, ending a twenty-plus year career in education, and have spent time thinking about what I want the next chapter of my life to look like. I found myself thinking back to a drawing exercise I did a few years ago that has made such an impact on my being willing to make major changes in my life.

Entering my mid-forties, I had come to a point where something just felt “off.” I wasn’t sleeping well, often waking at 3am with anxiety about real or imagined catastrophes. I was often stressed and short-tempered. I was gaining weight and my health wasn’t in the top-notch condition the way it had always bee…

Further Evidence for Cellular Senescence to Contribute to Atrial Fibrillation

Source https://www.fightaging.org/archives/2022/02/further-evidence-for-cellular-senescence-to-contribute-to-atrial-fibrillation/

Senescent cells accumulate with age, and their secretions provoke chronic inflammation and tissue dysfunction. With this in mind, researchers have shown that cellular senescence correlates with atrial fibrillation in older people. Here is a more recent demonstration of this relationship. I’m not aware of a study that shows senolytic therapy to remove senescent cells is a useful treatment for atrial fibrillation, but evaluation of this approach seems a good idea, both in aged animal models and in human patients.

Atrial fibrillation (…

Source https://www.fightaging.org/archives/2022/02/further-evidence-for-cellular-senescence-to-contribute-to-atrial-fibrillation/

Senescent cells accumulate with age, and their secretions provoke chronic inflammation and tissue dysfunction. With this in mind, researchers have shown that cellular senescence correlates with atrial fibrillation in older people. Here is a more recent demonstration of this relationship. I’m not aware of a study that shows senolytic therapy to remove senescent cells is a useful treatment for atrial fibrillation, but evaluation of this approach seems a good idea, both in aged animal models and in human patients.

Atrial fibrillation (…

Two Years of Calorie Restriction Produces Thymic Regrowth in Humans

Source https://www.fightaging.org/archives/2022/02/two-years-of-calorie-restriction-produces-thymic-regrowth-in-humans/

The thymus is responsible for turning thymocytes produced in the bone marrow into T cells of the adaptive immune system, in a complicated process of selection. This system is highly productive in youth, but active thymic tissue atrophies with age. This occurs for reasons that are far from fully explored, but may involve complex systemic issues related to rising inflammation and <a href="https://www.fightaging.org/archives/2021/09/dendritic-cells-migrate-to-th…

Source https://www.fightaging.org/archives/2022/02/two-years-of-calorie-restriction-produces-thymic-regrowth-in-humans/

The thymus is responsible for turning thymocytes produced in the bone marrow into T cells of the adaptive immune system, in a complicated process of selection. This system is highly productive in youth, but active thymic tissue atrophies with age. This occurs for reasons that are far from fully explored, but may involve complex systemic issues related to rising inflammation and <a href="https://www.fightaging.org/archives/2021/09/dendritic-cells-migrate-to-th…

Overwhelm: The Survival Guide

Source https://zenhabits.net/overwhelm-survival/

By Leo Babauta

Feeling overwhelmed with work and personal tasks is one of the biggest problems that the people I work with are facing.

It turns out, our lives can be pretty overwhelming.

There’s so much to do, never enough time to do it, and who knows what we should be focusing on? We’re always behind, barely treading water. That’s our usual experience of life, it seems.

What can we do? It turns out, there are some powerful things we can practice with overwhelm, and there are some practical things we can do as well.

What follows is meant to be a kind of survival guide — not only how to survive your overwhelming life, but how to turn it into a life of joy and impact.

There are a lot of things below, which ironically can be overwhelming. Pick one, and try it.

The Practical First Steps

The fir…

Source https://zenhabits.net/overwhelm-survival/

By Leo Babauta

Feeling overwhelmed with work and personal tasks is one of the biggest problems that the people I work with are facing.

It turns out, our lives can be pretty overwhelming.

There’s so much to do, never enough time to do it, and who knows what we should be focusing on? We’re always behind, barely treading water. That’s our usual experience of life, it seems.

What can we do? It turns out, there are some powerful things we can practice with overwhelm, and there are some practical things we can do as well.

What follows is meant to be a kind of survival guide — not only how to survive your overwhelming life, but how to turn it into a life of joy and impact.

There are a lot of things below, which ironically can be overwhelming. Pick one, and try it.

The Practical First Steps

The fir…

How Our Parents Impact Us: The Childhood Wounds That Shape Our Lives

Source https://tinybuddha.com/blog/how-our-parents-impact-us-the-childhood-wounds-that-shape-our-lives/

“The way we treat our children directly impacts what they believe about themselves.” ~Ariadne Brill

Growing up, I always felt odd. I often wondered what was wrong with me. I compared myself to my friends and always thought they had a better life than me. They had both parents still together, went on family vacations. It was not that I was jealous or bitter, it was just that they seemed to be ‘normal’ and happy. Whatever that means.

I never remember my parents being together. My parents divorced when I was two. I lived with my mother and older sister, who was eight years older than me.

My mother was a nurse, and we grew up in various nurses’ residences, as she did not have money to buy a house.

She was diagnosed with depression, and I remember ni…

Source https://tinybuddha.com/blog/how-our-parents-impact-us-the-childhood-wounds-that-shape-our-lives/

“The way we treat our children directly impacts what they believe about themselves.” ~Ariadne Brill

Growing up, I always felt odd. I often wondered what was wrong with me. I compared myself to my friends and always thought they had a better life than me. They had both parents still together, went on family vacations. It was not that I was jealous or bitter, it was just that they seemed to be ‘normal’ and happy. Whatever that means.

I never remember my parents being together. My parents divorced when I was two. I lived with my mother and older sister, who was eight years older than me.

My mother was a nurse, and we grew up in various nurses’ residences, as she did not have money to buy a house.

She was diagnosed with depression, and I remember ni…

Silent Migraine: The Not-So-Quiet Signs of This Condition

Source https://greatist.com/migraine/silent-migraine

Silent migraine is a migraine type that isn’t painful. But even without the headaches, silent migraine can be uncomfortable AF. It can trigger aura symptoms like blind spots, numbness, and nausea.

Here’s how to spot silent migraine and a rundown of the causes and best treatments.

person laying on ottoman in pink room with lamp over face
Ulas&Merve/Stocksy United

<h2 id="symptoms" data-toc-label="Symptoms" class="wp-block-heal…

Source https://greatist.com/migraine/silent-migraine

Silent migraine is a migraine type that isn’t painful. But even without the headaches, silent migraine can be uncomfortable AF. It can trigger aura symptoms like blind spots, numbness, and nausea.

Here’s how to spot silent migraine and a rundown of the causes and best treatments.

person laying on ottoman in pink room with lamp over face
Ulas&Merve/Stocksy United

<h2 id="symptoms" data-toc-label="Symptoms" class="wp-block-heal…

Senior Planet Habla con…Cheech Marin

Source https://seniorplanet.org/senior-planet-habla-con-cheech-marin/

Cheech Marin habla exclusivamente con Senior Planet sobre su interés en el arte Chicano, comó el envejece con actitud y la última vez que él vio a Tommy Chong.

The post Senior Planet Habla con…Cheech Marin appeared first on Senior Planet.

Source https://seniorplanet.org/senior-planet-habla-con-cheech-marin/

Cheech Marin habla exclusivamente con Senior Planet sobre su interés en el arte Chicano, comó el envejece con actitud y la última vez que él vio a Tommy Chong.

The post Senior Planet Habla con…Cheech Marin appeared first on Senior Planet.

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