Source https://www.fightaging.org/archives/2021/08/speculating-on-involvement-of-sirt1-and-sirt3-in-the-aging-of-the-heart/
In today’s research materials, scientists demonstrate that the combination of reduced SIRT1 and SIRT3 causes weakness in heart muscle via disruption of mitochondrial function. Mitochondria are the power plants of the cell, a herd of hundreds of bacteria-like organelles that are responsible for producing the chemical energy store molecule adenosine triphosphate (ATP) to power cellular operations. Impairment of mitochondrial function thus results in impaired cell function, a characteristic change observed in old tissues. Mitochondrial dynamics, the balance of fusion and <a href="h…
Source https://www.fightaging.org/archives/2021/08/speculating-on-involvement-of-sirt1-and-sirt3-in-the-aging-of-the-heart/
In today’s research materials, scientists demonstrate that the combination of reduced SIRT1 and SIRT3 causes weakness in heart muscle via disruption of mitochondrial function. Mitochondria are the power plants of the cell, a herd of hundreds of bacteria-like organelles that are responsible for producing the chemical energy store molecule adenosine triphosphate (ATP) to power cellular operations. Impairment of mitochondrial function thus results in impaired cell function, a characteristic change observed in old tissues. Mitochondrial dynamics, the balance of fusion and <a href="h…
Source https://www.nerdfitness.com/blog/megan-lost-15-pounds-by-eating-more/
“I thought it was crazy at first when my coach told me to start eating more, when my goal was to lose weight.
But then I tried it. And it worked.
‘Reverse dieting’ actually helped me lose the last few stubborn pounds.”
This is Megan, a member of Nerd Fitness Coaching who is celebrating hitting her goal weight.
What’s so interesting about her story is how she did it.
Megan’s coach saw that she was hitting a wall with her lower-calorie diet.
Instead of continuing, Coach Evan proposed they try something different: eat more.
Unconve…
Source https://www.nerdfitness.com/blog/megan-lost-15-pounds-by-eating-more/
“I thought it was crazy at first when my coach told me to start eating more, when my goal was to lose weight.
But then I tried it. And it worked.
‘Reverse dieting’ actually helped me lose the last few stubborn pounds.”
This is Megan, a member of Nerd Fitness Coaching who is celebrating hitting her goal weight.
What’s so interesting about her story is how she did it.
Megan’s coach saw that she was hitting a wall with her lower-calorie diet.
Instead of continuing, Coach Evan proposed they try something different: eat more.
Unconve…
Source https://www.theminimalists.com/p303/
By Joshua Fields Millburn & Ryan Nicodemus · Follow: Facebook, Twitter, Instagram
In this episode of The Minimalists Podcast, Joshua and Ryan talk about how to avoid recluttering our lives with new possessions, burdens, and obligations once we’…
Source https://www.theminimalists.com/p303/
By Joshua Fields Millburn & Ryan Nicodemus · Follow: Facebook, Twitter, Instagram
In this episode of The Minimalists Podcast, Joshua and Ryan talk about how to avoid recluttering our lives with new possessions, burdens, and obligations once we’…
Source https://www.fightaging.org/archives/2021/08/engineering-chimeric-antigen-receptor-t-cells-to-activate-only-when-ultrasound-energy-is-applied/
Providing a patient’s T cells with a receptor to match the surface characteristics of the patient’s cancer cells is proving to work quite well for some types of cancer. Unfortunately the match is never perfectly specific for cancerous cells, and chimeric antigen receptor T cells (CAR-T cells) can do a lot of damage to healthy tissue in many of the desired scenarios for treatment. Researchers here report on one of a number of presently explored approaches to limit the activation of CAR-T cells to only the cancerous tissue of interest, thereby making the therapy more viable.
New work addresses a longstanding problem in the field of cancer immunotherapy: how to make chimeric antigen receptor (CAR) T-cell therap…
Source https://www.fightaging.org/archives/2021/08/engineering-chimeric-antigen-receptor-t-cells-to-activate-only-when-ultrasound-energy-is-applied/
Providing a patient’s T cells with a receptor to match the surface characteristics of the patient’s cancer cells is proving to work quite well for some types of cancer. Unfortunately the match is never perfectly specific for cancerous cells, and chimeric antigen receptor T cells (CAR-T cells) can do a lot of damage to healthy tissue in many of the desired scenarios for treatment. Researchers here report on one of a number of presently explored approaches to limit the activation of CAR-T cells to only the cancerous tissue of interest, thereby making the therapy more viable.
New work addresses a longstanding problem in the field of cancer immunotherapy: how to make chimeric antigen receptor (CAR) T-cell therap…
Source https://minimalistbaker.com/creamy-vegan-pink-pasta-30-minutes/
Pink pasta?! When we heard about this creamy, vibrant dish, we knew we had to give a plant-based version a try! Spoiler alert? Major success!
Rich, savory tomato sauce pairs with vegan cashew cream and noodles for the most comforting bowl of goodness. Just 10 ingredients and 30 minutes required for this weeknight-friendly main or side. Let’s make pasta!
Recipe Inspiration: Penne alla Vodka
This vegan pink pasta was inspired by Female Foodie’s recipe, w…
Source https://minimalistbaker.com/creamy-vegan-pink-pasta-30-minutes/
Pink pasta?! When we heard about this creamy, vibrant dish, we knew we had to give a plant-based version a try! Spoiler alert? Major success!
Rich, savory tomato sauce pairs with vegan cashew cream and noodles for the most comforting bowl of goodness. Just 10 ingredients and 30 minutes required for this weeknight-friendly main or side. Let’s make pasta!
Recipe Inspiration: Penne alla Vodka
This vegan pink pasta was inspired by Female Foodie’s recipe, w…
Source https://seniorplanet.org/when-youre-the-alertee/
In an emergency, the ER needs more information than you think. Get the inside scoop here.
The post When You’re the “Alertee.” appeared first on Senior Planet.
…
Source https://seniorplanet.org/when-youre-the-alertee/
In an emergency, the ER needs more information than you think. Get the inside scoop here.
The post When You’re the “Alertee.” appeared first on Senior Planet.
…
Source http://feedproxy.google.com/~r/tinybuddha/~3/GEWdh9mZn80/
“I will not say: do not weep; for not all tears are an evil.” ~J.R.R. Tolkien, The Return of the King
Grief creeps up on you when you least expect it. It reminds you of the person you have lost when you’re out for coffee with friends, watching people hug their loved ones goodbye at the airport, and when you’re at home thinking about people you should call to check-in on.
Even when you think that enough time has passed for you to be over it, grief pulls at your heartstrings. You think about all the ways that life has changed, and your heart longs to have one last conversation with the person you have lost, one last hug, and one last shared memory.
A wise person once told me that when you love someone the hurt neve…
Source http://feedproxy.google.com/~r/tinybuddha/~3/GEWdh9mZn80/
“I will not say: do not weep; for not all tears are an evil.” ~J.R.R. Tolkien, The Return of the King
Grief creeps up on you when you least expect it. It reminds you of the person you have lost when you’re out for coffee with friends, watching people hug their loved ones goodbye at the airport, and when you’re at home thinking about people you should call to check-in on.
Even when you think that enough time has passed for you to be over it, grief pulls at your heartstrings. You think about all the ways that life has changed, and your heart longs to have one last conversation with the person you have lost, one last hug, and one last shared memory.
A wise person once told me that when you love someone the hurt neve…
