Source https://www.fightaging.org/archives/2022/11/successful-treatment-of-aging-is-a-goal-of-great-importance-to-public-health/
Why has the tone of writing by ethicists on the topic of treating aging as a medical condition, with consequent extension of health human life span, shifted from from hostility to endorsement over the last twenty years? One possibility is that while a technological capability is thought to be a far future possibility, or unattainable, only those with an ax to grind will talk about it. The years since the turn of the century have seen tremendous progress towards implementing therapies capable of addressing mechanisms of aging, and in lockstep with that the scientific community, and a small but sizable fraction of the public at large, have come to understand that rejuvenation and slowing of aging are viable near future goals. Some of those people are ethicists lacking an ax to grind, and some of t…
Source https://www.fightaging.org/archives/2022/11/successful-treatment-of-aging-is-a-goal-of-great-importance-to-public-health/
Why has the tone of writing by ethicists on the topic of treating aging as a medical condition, with consequent extension of health human life span, shifted from from hostility to endorsement over the last twenty years? One possibility is that while a technological capability is thought to be a far future possibility, or unattainable, only those with an ax to grind will talk about it. The years since the turn of the century have seen tremendous progress towards implementing therapies capable of addressing mechanisms of aging, and in lockstep with that the scientific community, and a small but sizable fraction of the public at large, have come to understand that rejuvenation and slowing of aging are viable near future goals. Some of those people are ethicists lacking an ax to grind, and some of t…
Source https://www.fightaging.org/archives/2022/11/better-understanding-the-outcome-of-destroying-and-rebuilding-the-immune-system/
The use of chemotherapy to destroy as much of the peripheral immune system as possible, followed by some form of stem cell transplant to rebuild it, has been used for some years as a way to treat multiple sclerosis. In this autoimmune condition, the problem resides in the immune memory, and getting rid of that memory is the solution. The only approach currently demonstrated to work is this somewhat drastic treatment, and the balance of risk and cost means that it is only used for severe diseases such …
Source https://www.fightaging.org/archives/2022/11/better-understanding-the-outcome-of-destroying-and-rebuilding-the-immune-system/
The use of chemotherapy to destroy as much of the peripheral immune system as possible, followed by some form of stem cell transplant to rebuild it, has been used for some years as a way to treat multiple sclerosis. In this autoimmune condition, the problem resides in the immune memory, and getting rid of that memory is the solution. The only approach currently demonstrated to work is this somewhat drastic treatment, and the balance of risk and cost means that it is only used for severe diseases such …
Source https://seniorplanet.org/caregiving-for-caregivers/
Caregiving is difficult, but caregivers can learn tips to ease burnout – and comment on a National Strategy to Support Caregivers.
The post Caregiving for Caregivers appeared first on Senior Planet from AARP.
…
Source https://seniorplanet.org/caregiving-for-caregivers/
Caregiving is difficult, but caregivers can learn tips to ease burnout – and comment on a National Strategy to Support Caregivers.
The post Caregiving for Caregivers appeared first on Senior Planet from AARP.
…
Source https://www.fightaging.org/archives/2022/11/how-mitochondria-selectively-remove-damaged-mitochondrial-dna/
Mitochondrial DNA becomes damaged more readily than nuclear DNA, as the systems of DNA repair in mitochondria are less effective, and the DNA structures are less well protected. Some forms of mitochondrial DNA damage can cause mitochondria to become dysfunction while also replicating more efficiently than their peers, leading to pathological cells overtaken by pathological mitochondria that cause damage to their surroundings. As an opposing force, there appear to be ways in which mitochondria can selectively eliminate damaged DNA under some circumstances. Can these mechanisms be meaningfully enhanced to reduce mitochondrial DNA damage an…
Source https://www.fightaging.org/archives/2022/11/how-mitochondria-selectively-remove-damaged-mitochondrial-dna/
Mitochondrial DNA becomes damaged more readily than nuclear DNA, as the systems of DNA repair in mitochondria are less effective, and the DNA structures are less well protected. Some forms of mitochondrial DNA damage can cause mitochondria to become dysfunction while also replicating more efficiently than their peers, leading to pathological cells overtaken by pathological mitochondria that cause damage to their surroundings. As an opposing force, there appear to be ways in which mitochondria can selectively eliminate damaged DNA under some circumstances. Can these mechanisms be meaningfully enhanced to reduce mitochondrial DNA damage an…
Source https://seniorplanet.org/how-to-find-the-best-cyber-monday-deals/
Get the scoop on how to find the best online shopping holiday deals on Amazon ahead of Cyber Monday.
The post How to Find the Best Cyber Monday Deals appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/how-to-find-the-best-cyber-monday-deals/
Get the scoop on how to find the best online shopping holiday deals on Amazon ahead of Cyber Monday.
The post How to Find the Best Cyber Monday Deals appeared first on Senior Planet from AARP.
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Source https://www.fightaging.org/archives/2022/11/does-the-gut-microbiome-contribute-to-frailty-via-oxidative-stress/
The challenge in understanding degenerative aging is at this point less a matter of identifying mechanisms, and more a matter of establishing which of the many mechanisms involved in every specific aspect of aging are actually important. Cellular biochemistry is a complex interconnected web, and it is very hard to make changes to just one mechanism in isolation, so as to establish exactly its contribution. Now that biotechnology has advanced to the point at which near every biological mechanism is a viable target for intervention, it matters whether or not the research and development communities focus on the right targets, those that can produce meaningful benefits to patients.
Correlations are observed between the state of the gut microbiome and late life health, and the gut microbiom…
Source https://www.fightaging.org/archives/2022/11/does-the-gut-microbiome-contribute-to-frailty-via-oxidative-stress/
The challenge in understanding degenerative aging is at this point less a matter of identifying mechanisms, and more a matter of establishing which of the many mechanisms involved in every specific aspect of aging are actually important. Cellular biochemistry is a complex interconnected web, and it is very hard to make changes to just one mechanism in isolation, so as to establish exactly its contribution. Now that biotechnology has advanced to the point at which near every biological mechanism is a viable target for intervention, it matters whether or not the research and development communities focus on the right targets, those that can produce meaningful benefits to patients.
Correlations are observed between the state of the gut microbiome and late life health, and the gut microbiom…
Source https://www.theminimalists.com/open/
In this short video, Joshua, Ryan, and T.K. talk about one of their favorite rules for minimizing hidden clutter. Comment on YouTube and tell us about your favorite decluttering tip (we’ll feature the best tips on a future episode).
This is a standalone highlight from The Minimalists Private Podcast. If you’d like to help us take advantage of the YouTube algorithm, then please leave a “starter like” on YouTube.
P.S. We’re also sharing bite-sized podcasts on TikTok.
Subscribe to The Minimalists via
email.
The post Out-in-the-Open Decluttering Rule appeared first on <a rel="nofollow" href="https://www….
Source https://www.theminimalists.com/open/
In this short video, Joshua, Ryan, and T.K. talk about one of their favorite rules for minimizing hidden clutter. Comment on YouTube and tell us about your favorite decluttering tip (we’ll feature the best tips on a future episode).
This is a standalone highlight from The Minimalists Private Podcast. If you’d like to help us take advantage of the YouTube algorithm, then please leave a “starter like” on YouTube.
P.S. We’re also sharing bite-sized podcasts on TikTok.
Subscribe to The Minimalists via
email.
The post Out-in-the-Open Decluttering Rule appeared first on <a rel="nofollow" href="https://www….
Source https://tinybuddha.com/blog/stay-in-the-right-lane-let-yourself-slow-down-and-enjoy-life/
“I don’t want to get to the end of my life and find that I lived just the length of it. I want to have lived the width of it as well.” ~Diane Ackerman
Wow! My last weeks of my career. Though many days and weeks over the last thirty-four years have seemed to last forever, it truly is astonishing how fast time goes. And don’t we often try to make it go even faster?
Our jobs are stressful. We are often under tight time constraints and deadlines. We have clients and associates who want and need things yesterday.
We work in jobs we have very little control over. Add that to our daily responsibilities as parents, spouses, partners, friends, children to aging parents and—not to be forgotten—ourselves. It’s a lot.
Maybe you are like me. When I…
Source https://tinybuddha.com/blog/stay-in-the-right-lane-let-yourself-slow-down-and-enjoy-life/
“I don’t want to get to the end of my life and find that I lived just the length of it. I want to have lived the width of it as well.” ~Diane Ackerman
Wow! My last weeks of my career. Though many days and weeks over the last thirty-four years have seemed to last forever, it truly is astonishing how fast time goes. And don’t we often try to make it go even faster?
Our jobs are stressful. We are often under tight time constraints and deadlines. We have clients and associates who want and need things yesterday.
We work in jobs we have very little control over. Add that to our daily responsibilities as parents, spouses, partners, friends, children to aging parents and—not to be forgotten—ourselves. It’s a lot.
Maybe you are like me. When I…
Source https://minimalistbaker.com/lemon-herb-roasted-chicken-thighs/
Ever in the mood for roasted chicken but don’t want to go to the full effort? Us too! We have a remedy. Say hello to your NEW weeknight go-to: Lemon & Herb Roasted Chicken Thighs! All the tender meat, crispy skin, and satisfaction of roasted chicken, with much less work and half the time!
These chicken thighs are perfect for weeknights or meal prep yet elegant enough to be the centerpiece at a dinner party.
Lemon …
Source https://minimalistbaker.com/lemon-herb-roasted-chicken-thighs/
Ever in the mood for roasted chicken but don’t want to go to the full effort? Us too! We have a remedy. Say hello to your NEW weeknight go-to: Lemon & Herb Roasted Chicken Thighs! All the tender meat, crispy skin, and satisfaction of roasted chicken, with much less work and half the time!
These chicken thighs are perfect for weeknights or meal prep yet elegant enough to be the centerpiece at a dinner party.
Lemon …