Source https://www.fightaging.org/archives/2020/05/%CE%B1-synuclein-aggregation-impairs-autophagy-in-brain-tissue/
Age-related neurodegeneration is characterized by the aggregation of a small number of proteins, including α-synuclein, that can become altered in a manner that encourages other molecules of the same protein to alter in the same way. These altered forms of protein precipitate to form structures solid fibrils and deposits, surrounded by a halo of toxic biochemistry that impairs cell function. Today’s open access paper explores just one of the ways in which α-synuclein harms cells, in this case by downregulating the operation of autophagy.
Autophagy is the name given to a collection of cellular maintenance processes that are particularly important in long-lived cells such as the neurons of the <a href="https://en.wikipedia.org/wiki/Central_nerv…
Source https://www.fightaging.org/archives/2020/05/%CE%B1-synuclein-aggregation-impairs-autophagy-in-brain-tissue/
Age-related neurodegeneration is characterized by the aggregation of a small number of proteins, including α-synuclein, that can become altered in a manner that encourages other molecules of the same protein to alter in the same way. These altered forms of protein precipitate to form structures solid fibrils and deposits, surrounded by a halo of toxic biochemistry that impairs cell function. Today’s open access paper explores just one of the ways in which α-synuclein harms cells, in this case by downregulating the operation of autophagy.
Autophagy is the name given to a collection of cellular maintenance processes that are particularly important in long-lived cells such as the neurons of the <a href="https://en.wikipedia.org/wiki/Central_nerv…
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