A High Level Tour of the Landscape of Alzheimer's Drug Development

Source https://www.fightaging.org/archives/2022/06/a-high-level-tour-of-the-landscape-of-alzheimers-drug-development/

The brain is a very complex organ, and thus the age-related failures of brain function also tend to be very complex. Alzheimer’s disease receives the greatest attention from the research community, but is still only partially understood. The major focus of efforts over the past two decades has been on the clearance of amyloid-β aggregates from the brain, largely via immunotherapies, but a few other approaches have surfaced as well. Only in the past few years has this effort achieved success and resulted in large reductions in amyloid-β in patient brains, but unfortunately this did not result in a reversal of symptoms.

The <a href="https://en.wikipedia.o…

Source https://www.fightaging.org/archives/2022/06/a-high-level-tour-of-the-landscape-of-alzheimers-drug-development/

The brain is a very complex organ, and thus the age-related failures of brain function also tend to be very complex. Alzheimer’s disease receives the greatest attention from the research community, but is still only partially understood. The major focus of efforts over the past two decades has been on the clearance of amyloid-β aggregates from the brain, largely via immunotherapies, but a few other approaches have surfaced as well. Only in the past few years has this effort achieved success and resulted in large reductions in amyloid-β in patient brains, but unfortunately this did not result in a reversal of symptoms.

The <a href="https://en.wikipedia.o…

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