Combining Age-Slowing Interventions in Flies Doubles Life Span

Source https://www.fightaging.org/archives/2022/06/combining-age-slowing-interventions-in-flies-doubles-life-span/

Very little work takes place on combinations of interventions known to target mechanisms of aging. This is largely, I suspect, for reasons relating to intellectual property and control of later development. The work that does take place usually looks at approaches known or likely to have minimal effects in long-lived species such as our own, even while producing sizable gains in short-lived species, and this open access paper follows that trend.

It is unfortunate that short-lived species exhibit a pace of aging that is so much more reactive to the environment than that of long-lived species, as it has biased a great deal of research into directions, such as analysis of the beneficial response to calorie restriction, that cannot possibly greatly extend human li…

Source https://www.fightaging.org/archives/2022/06/combining-age-slowing-interventions-in-flies-doubles-life-span/

Very little work takes place on combinations of interventions known to target mechanisms of aging. This is largely, I suspect, for reasons relating to intellectual property and control of later development. The work that does take place usually looks at approaches known or likely to have minimal effects in long-lived species such as our own, even while producing sizable gains in short-lived species, and this open access paper follows that trend.

It is unfortunate that short-lived species exhibit a pace of aging that is so much more reactive to the environment than that of long-lived species, as it has biased a great deal of research into directions, such as analysis of the beneficial response to calorie restriction, that cannot possibly greatly extend human li…

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