Lygenesis works towards restoration of liver function by implanting liver organoids into lymph nodes, where they survive and undertake many of the normal functions of a liver. People have more lymph nodes than needed in many parts of the body, so some can be sacrificed in this way to gain improved function. This approach is in clinical development, and the company plans to attempt much the same process for the thymus, another important organ in which function does not depend all that much on location in the body. Researchers associated with Lygenesis here explore other parts of the body that are amenable to hosting implanted organoids, expanding the options for this clas…
Expanding the Options for Implantation of Functional Liver Organoids into the Body
Lygenesis works towards restoration of liver function by implanting liver organoids into lymph nodes, where they survive and undertake many of the normal functions of a liver. People have more lymph nodes than needed in many parts of the body, so some can be sacrificed in this way to gain improved function. This approach is in clinical development, and the company plans to attempt much the same process for the thymus, another important organ in which function does not depend all that much on location in the body. Researchers associated with Lygenesis here explore other parts of the body that are amenable to hosting implanted organoids, expanding the options for this clas…