Extracellular Vesicles from Young Mice Improve Health and Reduce Frailty in Old Mice

Source https://www.fightaging.org/archives/2021/08/extracellular-vesicles-from-young-mice-improve-health-and-reduce-frailty-in-old-mice/

Much of cell signaling is carried via extracellular vesicles, membrane-wrapped packages of molecules. Researchers are finding that delivery of extracellular vesicles harvested from stem cells may be a good replacement for first generation stem cell therapies, in which the transplanted cells produce benefits via signaling before dying. Extracellular vesicles are an easier, cheaper approach from a logistical point of view. Here, researchers show that only vesicles generated by stem cells from young mice are capable of producing an impact on frailty in old mice, an indication of the degree to which aging impacts cell signaling and function.

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