Greater MMP-2 Levels in a Population of Long-Lived Individuals

Source https://www.fightaging.org/archives/2020/06/greater-mmp-2-levels-in-a-population-of-long-lived-individuals/

A great many research groups are engaged in the search for distinct biochemistry in extremely old humans. How do older individuals survive where their peers did not, and can any of the answer to that question be turned into useful therapies? My suspicion is that there are no useful therapies to be found in the genetics and metabolism of exceptional human longevity: these people are still suffering a high burden of damage, and are greatly diminished in capacity. The differences they carry do not tend to swing the odds far, and epidemiological studies suggest that individual variation in genetics and metabolism is a tiny contribution compared to life-long lifestyle choices.

The matrix metalloproteinase (MMP) group of pro…

Source https://www.fightaging.org/archives/2020/06/greater-mmp-2-levels-in-a-population-of-long-lived-individuals/

A great many research groups are engaged in the search for distinct biochemistry in extremely old humans. How do older individuals survive where their peers did not, and can any of the answer to that question be turned into useful therapies? My suspicion is that there are no useful therapies to be found in the genetics and metabolism of exceptional human longevity: these people are still suffering a high burden of damage, and are greatly diminished in capacity. The differences they carry do not tend to swing the odds far, and epidemiological studies suggest that individual variation in genetics and metabolism is a tiny contribution compared to life-long lifestyle choices.

The matrix metalloproteinase (MMP) group of pro…

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