Several research groups and companies are working on in vivo applications of cellular reprogramming. Today’s research materials cover recent work from David Sinclair’s team showing off the use of reprogramming to produce regeneration of damaged nervous system tissue in the eye and optic nerve. Glaucoma is a condition in which rising pressure in the eyeball progressively harms the retina and optic nerve. Since nerve tissue doesn’t regenerate well in mammals, loss of vision is irreversible. This is one of many conditions for which the ability to regenerate nerve tissue would be a great benefit.
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In Vivo Reprogramming Reverses Vision Loss and Damage in a Mouse Model of Glaucoma
Several research groups and companies are working on in vivo applications of cellular reprogramming. Today’s research materials cover recent work from David Sinclair’s team showing off the use of reprogramming to produce regeneration of damaged nervous system tissue in the eye and optic nerve. Glaucoma is a condition in which rising pressure in the eyeball progressively harms the retina and optic nerve. Since nerve tissue doesn’t regenerate well in mammals, loss of vision is irreversible. This is one of many conditions for which the ability to regenerate nerve tissue would be a great benefit.
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