Inflammatory Microglia in the Brain as a Contribution to Cardiovascular Disease

Source https://www.fightaging.org/archives/2022/06/inflammatory-microglia-in-the-brain-as-a-contribution-to-cardiovascular-disease/

Microglia are innate immune cells of the brain, and their dysfunction is implicated in the progression of neurodegenerative conditions. Microglia become overly activated and inflammatory with age, likely a reaction to cell damage and dysfunction resulting from mechanisms of aging, as well as to a rising background level of chronic inflammatory signaling characteristic of the aged environment, which the microglia then amplify. Here, researchers discuss how these pro-inflammatory changes in the brain can influence the development of cardiovascular disease outside the brain.

Microglia, commonly known as brain-resident immune cells, are ubiquitously present in the <a href="https://en.wikipedia.org/wiki/Central_…

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