Loss of Capillary Density as a Hallmark of Aging

Source https://www.fightaging.org/archives/2021/02/loss-of-capillary-density-as-a-hallmark-of-aging/

In today’s open access paper, researchers add to the present body of evidence for loss of capillary density to be an important mechanism of aging. All tissues are packed with capillaries, hundreds passing through every square millimeter in cross-section. This density is lost with age, and that reduces the supply of nutrients and oxygen to cells. Like the raised blood pressure of hypertension, loss of capillary density is a fair way downstream from the molecular damage that causes aging. Also like hypertension, loss of capillary density may make a large enough contribution to further tissue damage and dysfunction to be worth targeting independently of its cause…

Source https://www.fightaging.org/archives/2021/02/loss-of-capillary-density-as-a-hallmark-of-aging/

In today’s open access paper, researchers add to the present body of evidence for loss of capillary density to be an important mechanism of aging. All tissues are packed with capillaries, hundreds passing through every square millimeter in cross-section. This density is lost with age, and that reduces the supply of nutrients and oxygen to cells. Like the raised blood pressure of hypertension, loss of capillary density is a fair way downstream from the molecular damage that causes aging. Also like hypertension, loss of capillary density may make a large enough contribution to further tissue damage and dysfunction to be worth targeting independently of its cause…

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