Much Yet to Establish Regarding the Role of Regulatory T Cells in Immune System Aging

Source https://www.fightaging.org/archives/2022/09/much-yet-to-establish-regarding-the-role-of-regulatory-t-cells-in-immune-system-aging/

Regulatory T cells, as the name might suggest, are involved in controlling the immune response, particularly damping it down at the point at which it should resolve. They also prevent an inflammatory response from starting when it would be harmful or unnecessary, such as in response to self-antigens. A failure of regulatory T cell function is likely involved in autoimmunity, as well as in the chronic inflammation of aging.

As today’s open access paper notes, regulatory T cells may be both harmful and helpful in older individuals, attempting to suppress inappropriate inflammation, but also becoming dysfunctional in ways that both suppress appropriate immune responses to infection a…

Source https://www.fightaging.org/archives/2022/09/much-yet-to-establish-regarding-the-role-of-regulatory-t-cells-in-immune-system-aging/

Regulatory T cells, as the name might suggest, are involved in controlling the immune response, particularly damping it down at the point at which it should resolve. They also prevent an inflammatory response from starting when it would be harmful or unnecessary, such as in response to self-antigens. A failure of regulatory T cell function is likely involved in autoimmunity, as well as in the chronic inflammation of aging.

As today’s open access paper notes, regulatory T cells may be both harmful and helpful in older individuals, attempting to suppress inappropriate inflammation, but also becoming dysfunctional in ways that both suppress appropriate immune responses to infection a…

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