Physical Fitness Slows Accumulation of Senescent Cells to Better Maintain Vascular Function

Source https://www.fightaging.org/archives/2023/05/physical-fitness-slows-accumulation-of-senescent-cells-to-better-maintain-vascular-function/

To the degree that regular exercise and maintenance physical fitness preserve health in later life, it must be slowing the fundamental mechanisms of aging. One of those mechanisms is the accumulation of senescent cells, which emerges due to a growing imbalance between the pace of creation and pace of destruction. Exercise is known to improve autophagy, and this in turn slows the pace of creation of senescent cells. Exercise also improves immune function. Which of these effects are more important in the case of the age-related burden of senescent cells is an open question.

Blood vessels are key conduits for the transport of blood and circulating …

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