Polarization of Microglia to M2 as a Basis for Treating Neurodegenerative Conditions

Source https://www.fightaging.org/archives/2022/03/polarization-of-microglia-to-m2-as-a-basis-for-treating-neurodegenerative-conditions/

A good deal of evidence points to increased inflammatory activation of microglia in the brain, and consequent chronic inflammation of brain tissue, as an important component of neurodegenerative conditions. Some of these inflammatory microglia are senescent, and their clearance has been shown to be helpful in animal models, but the broader problem is an imbalance between pro-inflammatory <a hr…

Source https://www.fightaging.org/archives/2022/03/polarization-of-microglia-to-m2-as-a-basis-for-treating-neurodegenerative-conditions/

A good deal of evidence points to increased inflammatory activation of microglia in the brain, and consequent chronic inflammation of brain tissue, as an important component of neurodegenerative conditions. Some of these inflammatory microglia are senescent, and their clearance has been shown to be helpful in animal models, but the broader problem is an imbalance between pro-inflammatory <a hr…

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