SFRP1 as a Target for the Activation of Neural Progenitor Cells

Source https://www.fightaging.org/archives/2022/03/sfrp1-as-a-target-for-the-activation-of-neural-progenitor-cells/

Increased generation of new neurons in the brain, upregulation of the process of neurogenesis, is an important goal for the field of regenerative medicine. It would likely improve brain function at all ages, but since neurogenesis declines with age as stem cell populations become less active, it would be of particular relevance to the aging brain. Thus researchers are looking for ways to influence the regulatory systems controlling quiescence versus activity in neural stem cells and progenitor cells, in order to override the natural response to the aged tissue environment and put them back to work.

In most mammals, …

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