Today’s open access paper discusses a way to slow neuromuscular junction aging, and thereby age-related loss of muscle function. Loss of muscle strength, dynapenia, and loss of muscle mass, sarcopenia, are characteristic of aging. These declines contribute to age-related frailty directly and evidently, but it is also worth noting that muscle tissue is metabolically active, and appears to contribute beneficial signal molecules to the circulation, collectively called myokines. Loss of muscle tissue likely has a harmful effect on overall me…
Slowing Loss of Motor Function by Inhibiting VPS-34 in the Neuromuscular Junction
Today’s open access paper discusses a way to slow neuromuscular junction aging, and thereby age-related loss of muscle function. Loss of muscle strength, dynapenia, and loss of muscle mass, sarcopenia, are characteristic of aging. These declines contribute to age-related frailty directly and evidently, but it is also worth noting that muscle tissue is metabolically active, and appears to contribute beneficial signal molecules to the circulation, collectively called myokines. Loss of muscle tissue likely has a harmful effect on overall me…