Source https://www.fightaging.org/archives/2019/10/the-resurrection-of-aducanumab-doesnt-change-the-picture-for-amyloid-%CE%B2-clearance-in-alzheimers-disease/
It took a long time and many failed attempts for the research community to get to the point at which amyloid-β could be successfully cleared from the brains of Alzheimer’s patients. Unfortunately, the data to date strongly suggests that this isn’t an effective approach to therapy, at least not on its own, even though it is clearly the case that the increased levels of amyloid-β in the aging brain should be removed. It is a characteristic difference between old brain tissue and young brain tissue, and there is plenty of evidence for it to be harmful.
This failure to achieve clinical success may be because amyloid-β aggregation ceases to be an important factor in later stage disease, once <a href="https://en.wiki…
Source https://www.fightaging.org/archives/2019/10/the-resurrection-of-aducanumab-doesnt-change-the-picture-for-amyloid-%CE%B2-clearance-in-alzheimers-disease/
It took a long time and many failed attempts for the research community to get to the point at which amyloid-β could be successfully cleared from the brains of Alzheimer’s patients. Unfortunately, the data to date strongly suggests that this isn’t an effective approach to therapy, at least not on its own, even though it is clearly the case that the increased levels of amyloid-β in the aging brain should be removed. It is a characteristic difference between old brain tissue and young brain tissue, and there is plenty of evidence for it to be harmful.
This failure to achieve clinical success may be because amyloid-β aggregation ceases to be an important factor in later stage disease, once <a href="https://en.wiki…
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