The Tight Junctions of the Blood-Brain Barrier in Aging and Neurodegeneration

Source https://www.fightaging.org/archives/2019/11/the-tight-junctions-of-the-blood-brain-barrier-in-aging-and-neurodegeneration/

Today’s open access paper is a review of the tight junction structures of the blood-brain barrier in aging and neurodegeneration. The blood-brain barrier is a structure of specialized cells that lines the blood vessels that pass through central nervous system tissue. The barrier allows only certain molecules and cells to pass between blood vessels and the central nervous system, thus preserving its separation from the rest of the body. Unfortunately the integrity of the blood-brain barrier breaks down with advancing age, and the entry of unwanted molecules and cells into the brain then contributes to inflammation and tissue dysfunction.

A number of studies ha…

Source https://www.fightaging.org/archives/2019/11/the-tight-junctions-of-the-blood-brain-barrier-in-aging-and-neurodegeneration/

Today’s open access paper is a review of the tight junction structures of the blood-brain barrier in aging and neurodegeneration. The blood-brain barrier is a structure of specialized cells that lines the blood vessels that pass through central nervous system tissue. The barrier allows only certain molecules and cells to pass between blood vessels and the central nervous system, thus preserving its separation from the rest of the body. Unfortunately the integrity of the blood-brain barrier breaks down with advancing age, and the entry of unwanted molecules and cells into the brain then contributes to inflammation and tissue dysfunction.

A number of studies ha…

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