Both the innate and adaptive immune systems decline in function and run awry with age. Taken as a whole, researchers view this as the combination of inflammaging and immunosenescence. Without delving into the details, inflammaging is chronic, unresolved inflammatory signaling, an overactivation of the immune system that produces harmful changes in cell behavior throughout the body, while immunosenescence is a decline in the effectiveness of the immune response, leaving an individual more vulnerable to pathogens</…
Trained Immunity Improves Function in Aged Innate Immune Cells
Both the innate and adaptive immune systems decline in function and run awry with age. Taken as a whole, researchers view this as the combination of inflammaging and immunosenescence. Without delving into the details, inflammaging is chronic, unresolved inflammatory signaling, an overactivation of the immune system that produces harmful changes in cell behavior throughout the body, while immunosenescence is a decline in the effectiveness of the immune response, leaving an individual more vulnerable to pathogens</…