Fifty years ago, at Marine Corps Base Camp Lejeune on the coast of North Carolina, Pete Egoscue began a quiet revolution in understanding our body’s posture and its relationship to pain.
It would be another seven years before he got his first clients, and another 11 before he opened his first clinic in San Diego. Today, he has 30 clinics across the world, millions of clients (including an impressive roster of professional athletes) functioning pain-free, and six best-selling books to his credit, with a seventh due out this week, a revised and updated version of his first, Pain Free.
Fifty years ago, at Marine Corps Base Camp Lejeune on the coast of North Carolina, Pete Egoscue began a quiet revolution in understanding our body’s posture and its relationship to pain.
It would be another seven years before he got his first clients, and another 11 before he opened his first clinic in San Diego. Today, he has 30 clinics across the world, millions of clients (including an impressive roster of professional athletes) functioning pain-free, and six best-selling books to his credit, with a seventh due out this week, a revised and updated version of his first, Pain Free.
Rockfish species vary widely in lifespan. Some even exhibit negligible senescence, showing few signs of aging across the majority of their long life spans. When closely related species have divergent life spans, there is perhaps the opportunity to learn something of how metabolism determines longevity. Accordingly, researchers here report on their study of varied rockfish species, in search of the differences in the molecular biology of cells that lead to differences in life span and pace of aging.
In a new study, researchers compare the genomes of nearly two-thirds of the known species of rockfish that inhabit coastal waters around the Pacific Ocean and uncover some o…
Rockfish species vary widely in lifespan. Some even exhibit negligible senescence, showing few signs of aging across the majority of their long life spans. When closely related species have divergent life spans, there is perhaps the opportunity to learn something of how metabolism determines longevity. Accordingly, researchers here report on their study of varied rockfish species, in search of the differences in the molecular biology of cells that lead to differences in life span and pace of aging.
In a new study, researchers compare the genomes of nearly two-thirds of the known species of rockfish that inhabit coastal waters around the Pacific Ocean and uncover some o…
A meaty meal can really hit the spot sometimes. But why settle for a fast food burger when you can have a quick and healthy meat feast at home! Here are nine delicious and nutritious beef recipes to try at home. And don’t worry, there’s something for all cooking levels and tastes!
How we picked the recipes
Obvi we only picked the best of the best for you, fam. Here’s how we chose.
Taste and nutrition. Each recipe is hella tasty and super satisfying. But they’re also nutritious and lighter than lots of other beefy meals.
Ingredients. We selected recipes that have easy-to-find and high quality ingredients.
Cooking level. You don’t have to be a Michelin star chef to make a delish …
A meaty meal can really hit the spot sometimes. But why settle for a fast food burger when you can have a quick and healthy meat feast at home! Here are nine delicious and nutritious beef recipes to try at home. And don’t worry, there’s something for all cooking levels and tastes!
How we picked the recipes
Obvi we only picked the best of the best for you, fam. Here’s how we chose.
Taste and nutrition. Each recipe is hella tasty and super satisfying. But they’re also nutritious and lighter than lots of other beefy meals.
Ingredients. We selected recipes that have easy-to-find and high quality ingredients.
Cooking level. You don’t have to be a Michelin star chef to make a delish …
Magnesium is a jack-of-all-trades nutrient. Your body needs it for muscle contraction, neurotransmitter release, energy production, nerve function, bone development… you get the idea, it’s a must-have for your health.
Magnesium is a jack-of-all-trades nutrient. Your body needs it for muscle contraction, neurotransmitter release, energy production, nerve function, bone development… you get the idea, it’s a must-have for your health.
Today’s open access editorial discusses one quite specific consequence of the age-related disruption of energy metabolism in cells. Mitochondria, the power plants of the cell, falter with age throughout the body, for complex reasons still under exploration. The proximate causes involve too little production of molecular machinery needed for the correct operation of the electron transport chain, or mitochondrial dynamics, in the first case leading to inefficient production of ATP and raised levels of reactive oxygen species, and in the second case leading to failure of quality control mechanisms intended to rem…
Today’s open access editorial discusses one quite specific consequence of the age-related disruption of energy metabolism in cells. Mitochondria, the power plants of the cell, falter with age throughout the body, for complex reasons still under exploration. The proximate causes involve too little production of molecular machinery needed for the correct operation of the electron transport chain, or mitochondrial dynamics, in the first case leading to inefficient production of ATP and raised levels of reactive oxygen species, and in the second case leading to failure of quality control mechanisms intended to rem…
At first glance, with only a few exceptions in the initial membership, the newly launched Longevity Biotech Association is an advocacy group for the small molecule, stress response upregulation faction within the development community focused on the treatment of aging as a medical condition. More advocacy for the concept and feasibility of treating aging is certainly a good thing, and it is welcome to see the arrival of new high-profile initiatives. A cautionary thought is that the only real merit of the small molecule stress response upregulation approach, mimicking thin slices of the beneficial metabolic response to exercise, calorie restriction, heat, cold, or…
At first glance, with only a few exceptions in the initial membership, the newly launched Longevity Biotech Association is an advocacy group for the small molecule, stress response upregulation faction within the development community focused on the treatment of aging as a medical condition. More advocacy for the concept and feasibility of treating aging is certainly a good thing, and it is welcome to see the arrival of new high-profile initiatives. A cautionary thought is that the only real merit of the small molecule stress response upregulation approach, mimicking thin slices of the beneficial metabolic response to exercise, calorie restriction, heat, cold, or…
“Intuition is the whisper of the soul.” ~Jiddu Krishnamurti
“I can’t believe they are taking her side over mine. I gave this job so many years, and she decides to walk in and mess it all up for me,” I said to my husband.
A few years back, when I was working full time at my corporate job, I got into a disagreement with a team member. It spiraled out of control to the point where my boss then had to have a sit-down with us. I was so humiliated and angry that he could not see my side.
They will realize when they lose you, whispered my ego.
That was when I decided to leave. I started to look for new jobs and got offers.
Now here is the thing—I did have a great job, I had a great team, no long hours…
“Intuition is the whisper of the soul.” ~Jiddu Krishnamurti
“I can’t believe they are taking her side over mine. I gave this job so many years, and she decides to walk in and mess it all up for me,” I said to my husband.
A few years back, when I was working full time at my corporate job, I got into a disagreement with a team member. It spiraled out of control to the point where my boss then had to have a sit-down with us. I was so humiliated and angry that he could not see my side.
They will realize when they lose you, whispered my ego.
That was when I decided to leave. I started to look for new jobs and got offers.
Now here is the thing—I did have a great job, I had a great team, no long hours…
UNITY Biotechnology recently reported positive results for their senolytic drug candidate UBX1325, probably derived from navitoclax. Senolytic therapies selectively destroy senescent cells in aged tissues, reducing their inflammatory signaling and contribution to tissue dysfunction. In this case, macular degeneration patients showed improved visual function after treatment, though one should wait for a larger study group before calling this an unqualified success. UNITY Biotechnology’s trials are essentially testing the thesis that localized removal of senescent cells can address pathology, and thus low, localized doses of chemotherapeutic-derived senolytic drugs can be used, minimizing side-effects. In this case, the senolytic is injected into the…
UNITY Biotechnology recently reported positive results for their senolytic drug candidate UBX1325, probably derived from navitoclax. Senolytic therapies selectively destroy senescent cells in aged tissues, reducing their inflammatory signaling and contribution to tissue dysfunction. In this case, macular degeneration patients showed improved visual function after treatment, though one should wait for a larger study group before calling this an unqualified success. UNITY Biotechnology’s trials are essentially testing the thesis that localized removal of senescent cells can address pathology, and thus low, localized doses of chemotherapeutic-derived senolytic drugs can be used, minimizing side-effects. In this case, the senolytic is injected into the…